Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849864 | 0.81 | RAB9A (0.47) | RAB9ANPC1KDM4EGLAMAPT | |
| SCHEMBL4969955 | 0.81 | RAB9A (0.47) | RAB9ANPC1KDM4EGLAMAPT | |
| SCHEMBL5850108 | 0.77 | KDM4E (0.42) | RAB9ANPC1KDM4EGLAMAPT | |
| SCHEMBL11269374 | 0.71 | RAB9A (0.48) | RAB9ANPC1KDM4EGLAMAPT | |
| SCHEMBL4968860 | 0.70 | GAA (0.61) | RAB9ANPC1KDM4EGLAMAPT | |
| Hydrochloric Acid SCHEMBL5851393 | 0.69 | GAA (0.59) | KDM4EGLAMAPTALDH1A1MAPK1 | |
| SCHEMBL10642658 | 0.68 | MAPT (0.47) | RAB9ANPC1KDM4EGLAMAPT | |
| SCHEMBL17303450 | 0.68 | MAPT (0.48) | RAB9ANPC1KDM4EGLAMAPT | |
| SCHEMBL5849893 | 0.68 | MAPT (0.78) | RAB9ANPC1KDM4EMAPTL3MBTL1 | |
| SCHEMBL9745242 | 0.67 | RAB9A (0.44) | RAB9ANPC1KDM4EGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048827-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | disclosed |