SCHEMBL5849902

SCHEMBL5849902

O=C(O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C(=O)OCl

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.40
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL990565 0.90 CES2 (0.39) CES2CES1
SCHEMBL28622150 0.88 KDM4E (0.33) HTTCES2CES1KDM4EALDH1A1
SCHEMBL8564289 0.85 CES2 (0.33) CES2CES1
SCHEMBL29431520 0.82 HTT (0.50) HTTCES2CES1KDM4EALDH1A1
SCHEMBL27772 0.82 HTT (0.50) HTTCES2CES1KDM4EALDH1A1
SCHEMBL27283856 0.81 HTT (0.40) HTTCES2CES1KDM4EALDH1A1
SCHEMBL28410963 0.79 CYP1A2 (0.33) KDM4EALDH1A1HSD17B10DPP4
SCHEMBL5336516 0.79 CA12 (0.40) HTTKDM4EALDH1A1HSD17B10
SCHEMBL5693960 0.79 HTT (0.48) HTTCES2CES1KDM4EALDH1A1
SCHEMBL3630379 0.79 HTT (0.48) HTTCES2CES1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153645-B2 Silver salt photo-thermal photographic dry imaging material, an image recording method and an image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2006-12-26 US disclosed
US-20050032010-A1 Silver salt photo-thermal photographic dry imaging material, an image recording method and an image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-02-10 US disclosed
EP-1505436-A1 A silver salt photothermographic dry imaging material Konica Minolta Medical & Graphic, Inc. (JP) 2005-02-09 EP disclosed