Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.53 |
| ▸ | CTSL | P07711 | 9/20 | 0.53 |
| ▸ | CTSS | P25774 | 6/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849923 | 0.84 | CTSK (0.52) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848350 | 0.84 | CTSK (0.51) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848318 | 0.83 | CTSK (0.54) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848792 | 0.83 | CTSK (0.54) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5850470 | 0.83 | CTSK (0.54) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848096 | 0.83 | CTSK (0.54) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5849048 | 0.82 | CTSK (0.49) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848122 | 0.82 | CTSK (0.51) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5850357 | 0.82 | CHRM2 (0.45) | CTSKCTSL | |
| SCHEMBL5850056 | 0.81 | CTSK (0.50) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008938-B2 | Benzene-fused heteroring derivatives and pharmaceutical agents comprising the same as active ingredient | NOKIA CORPORATION (FI) | 2006-03-07 | — | — | US | disclosed |
| EP-1254898-A1 | BENZENE-FUSED HETEROCYCLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-06 | — | — | EP | disclosed |