Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.54 |
| ▸ | CTSS | P25774 | 7/20 | 0.52 |
| ▸ | CTSL | P07711 | 6/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850470 | 1.00 | CTSK (0.54) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5848792 | 1.00 | CTSK (0.54) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5848318 | 1.00 | CTSK (0.54) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5849141 | 0.92 | CTSK (0.50) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5848294 | 0.90 | CTSS (0.51) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5848116 | 0.86 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5848783 | 0.86 | DRD2 (0.48) | — | |
| SCHEMBL5848165 | 0.85 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5850136 | 0.85 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5848401 | 0.85 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809092-B2 | 1,3,4,5-TETRAHYDRO-2H-2-BENZAZEPIN-2-YL DERIVATIVES; CYSTEINE PROTEASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-10-26 | — | — | US | claimed |
| EP-1254898-A1 | BENZENE-FUSED HETEROCYCLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-06 | — | — | EP | claimed |
| US-7008938-B2 | Benzene-fused heteroring derivatives and pharmaceutical agents comprising the same as active ingredient | NOKIA CORPORATION (FI) | 2006-03-07 | — | — | US | disclosed |