Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 7/20 | 0.33 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.33 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473497 | 0.77 | FDPS (0.43) | FDPSMETAP1PLA2G2ASMPD1CYP3A4 | |
| SCHEMBL5852227 | 0.76 | TSHR (0.36) | — | |
| SCHEMBL6057471 | 0.74 | PGK1 (0.30) | — | |
| SCHEMBL29145530 | 0.73 | FDPS (0.40) | FDPSMETAP1PLA2G2ASMPD1CYP3A4 | |
| SCHEMBL27423909 | 0.73 | CYP3A4 (0.62) | FDPSPLA2G2ACYP3A4L3MBTL1 | |
| SCHEMBL9797401 | 0.73 | SGPL1 (0.54) | FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL11392172 | 0.73 | PGK1 (0.32) | PLA2G2A | |
| SCHEMBL11415795 | 0.73 | PGK1 (0.32) | PLA2G2A | |
| SCHEMBL5850398 | 0.72 | — | — | |
| SCHEMBL4625317 | 0.72 | LPAR3 (0.51) | P2RY10GPR34PLA2G2CLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |