Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.79 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 3/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.60 |
| ▸ | F7 | P08709 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | F3 | P13726 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587350 | 0.89 | NPC1 (1.00) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL446619 | 0.89 | NPC1 (1.00) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL28210414 | 0.87 | NPC1 (0.96) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL27500072 | 0.87 | USP2 (0.70) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL15296270 | 0.87 | NPC1 (0.69) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL4486564 | 0.87 | AHR (0.70) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL856313 | 0.87 | AHR (0.70) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL3462787 | 0.87 | AHR (0.70) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL2461812 | 0.85 | NPC1 (0.61) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL20475484 | 0.85 | NPC1 (0.61) | NPC1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233922-B2 | Process for producing N-(hetero)arylazoles | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| US-9233922-B2 | Process for producing N-(hetero)arylazoles | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| EP-2736881-B1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO PERFUMERY CO LTD (JP) | 2015-10-07 | — | — | EP | disclosed |
| EP-2736881-B1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO PERFUMERY CO LTD (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-20140371461-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-12-18 | — | — | US | disclosed |
| US-20140371461-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-12-18 | — | — | US | disclosed |
| WO-2013032035-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-03-07 | — | — | WO | disclosed |
| US-7056348-B2 | 5-aryl-1,3,3-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibers | WELLA AG (DE) | 2006-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371461-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | CYP3A4, HCN4, PPOX | NPC1 3396/4885CA12 2762/4885CA1 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.