Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 4/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587350 | 1.00 | NPC1 (1.00) | NPC1GLO1CA1CA2CA12 | |
| SCHEMBL28210414 | 0.98 | NPC1 (0.96) | NPC1GLO1CA1CA2CA12 | |
| SCHEMBL20120884 | 0.96 | NPC1 (0.92) | NPC1GLO1CA1CA2CA12 | |
| SCHEMBL5850255 | 0.89 | NPC1 (0.79) | NPC1CA1CA2CA12CA9 | |
| SCHEMBL23095150 | 0.87 | NPC1 (0.75) | NPC1GLO1CA1CA2CA12 | |
| SCHEMBL22178786 | 0.86 | NPC1 (0.76) | NPC1GLO1CA1CA2CA12 | |
| SCHEMBL20179811 | 0.86 | NPC1 (0.74) | NPC1GLO1CA1CA2CA12 | |
| SCHEMBL12069204 | 0.86 | NPC1 (0.74) | NPC1GLO1CA1CA2CA12 | |
| SCHEMBL16598039 | 0.84 | NPC1 (0.71) | NPC1GLO1CA1CA2CA12 | |
| SCHEMBL2526465 | 0.84 | NPC1 (0.71) | NPC1GLO1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003165-B | A kind of synthetic method of 5,11- dihydro -5- Phenylindole simultaneously [3,2-b] carbazole | 河南省科学院化学研究所有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-108358830-A | A kind of 4,5- benzindoles compound and its application that shines | 上海道亦化工科技有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-108003165-A | A kind of synthetic method of 5,11- dihydros -5- Phenylindoles simultaneously [3,2-b] carbazole | 河南省科学院化学研究所有限公司 | 2018-05-08 | — | — | CN | claimed |
| CN-105623648-B | One kind is based on the sour cyanines colorimetric probe of the asymmetric side of benzindole and anil, preparation method and application | 常州大学 | 2017-10-20 | — | — | CN | claimed |
| CN-106631979-A | Indocyanine green, and preparation method and application thereof | 北京数字精准医疗科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-1092765-A | New tryptamine analogues and preparation method thereof and purposes | SMITHKLINE BEECHAM PLC (GB) | 1994-09-28 | — | — | CN | claimed |
| US-20250263760-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-08-21 | — | — | US | disclosed |
| US-12319946-B2 | Methods for producing modified bacteria for production of nitroaromatics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-06-03 | — | — | US | disclosed |
| CN-119822910-A | Method for catalyzing heterogeneous reduction of nitrogen-containing heterocyclic compound by using magnesium metal | 延安大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-119409622-A | Benzocarbazole derivative and synthetic method and application thereof | 南宁师范大学 | 2025-02-11 | — | — | CN | disclosed |
| US-20240409535-A1 | SOLID FORMS OF 3-((1R,3R)-1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)AZETIDIN-3-YL)AMINO)PHENYL)-3-METHYL-1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOL-2-YL)-2,2-DIFLUOROPROPAN-1-OL AND PROCESSES FOR PREPARING FUSED TRICYCLIC COMPOUNDS COMPRISING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY, INCLUDING METHODS OF THEIR USE | GENENTECH, INC. (US) | 2024-12-12 | — | — | US | disclosed |
| US-12150447-B2 | Plant growth regulator | UNIVERSITY OF WASHINGTON (US) | 2024-11-26 | — | — | US | disclosed |
| EP-4447954-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | Icahn School of Medicine at Mount Sinai (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-1992004321-A1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-03-19 | — | — | WO | disclosed |
| US-4973706-A | OXIDATION OF INDOLE WITH HYDROPEROXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-11-27 | — | — | US | disclosed |
| WO-1990010667-A1 | COMPOSITION OF RECYCLED POLYETHYLENE TEREPHTHALATE AND METHOD OF MAKING RIGID FOAMED ARTICLES FROM IT | TISSLAN S.A. (CH) | 1990-09-20 | — | — | WO | disclosed |
| CN-1042553-A | The preparation method of indigo compound | MITSUI TOATSU CHEMICALS (JP) | 1990-05-30 | — | — | CN | disclosed |
| EP-0368508-A2 | Process for the preparation of indigo compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-16 | — | — | EP | disclosed |
| CN-1037527-A | The preparation method of indigo compound | MITSUI TOATSU CHEMICALS (JP) | 1989-11-29 | — | — | CN | disclosed |
| EP-0339887-A1 | Process for the preparation of indigo compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409535-A1 | SOLID FORMS OF 3-((1R,3R)-1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)AZETIDIN-3-YL)AMINO)PHENYL)-3-METHYL-1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOL-2-YL)-2,2-DIFLUOROPROPAN-1-OL AND PROCESSES FOR PREPARING FUSED TRICYCLIC COMPOUNDS COMPRISING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY, INCLUDING METHODS OF THEIR USE | TP53, DPYD, FLI1 | NPC1 1976/4885GLO1 2505/4885CA1 3447/4885 |
| US-12150447-B2 | Plant growth regulator | ING2, GHRHR, MYB | NPC1 4010/4885GLO1 779/4885CA1 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.