SCHEMBL5850544

SCHEMBL5850544

O=P(OCl)(OCCCl)OCCCl

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.74
CYP3A4 P08684 2/20 0.35
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11547470 0.94 ALDH1A1 (0.74) ALDH1A1CYP3A4TSHR
SCHEMBL26896 0.85 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHR
SCHEMBL7615526 0.84 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHR
Hydrochloric Acid SCHEMBL21956045 0.82 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHR
SCHEMBL499601 0.82 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHR
SCHEMBL4648149 0.80 ALDH1A1 (0.78) ALDH1A1CYP3A4TSHR
SCHEMBL9298387 0.78 ALDH1A1 (0.83) ALDH1A1CYP3A4TSHR
SCHEMBL30094709 0.78 ALDH1A1 (0.83) ALDH1A1CYP3A4TSHR
Phosphoric Acid SCHEMBL6229840 0.78 ALDH1A1 (0.83) ALDH1A1CYP3A4TSHR
SCHEMBL11256075 0.78 ALDH1A1 (0.83) ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed
EP-0937087-B1 MONOHYDROXY-TERMINATED PHOSPHATES AND THEIR USE AS FLAME RETARDANTS AKZO NOBEL NV (NL) 2003-09-10 EP disclosed
EP-0808840-B1 Process for preparing tribromoneopentyl chloroalkyl phosphates DAIHACHI CHEM IND (JP) 2002-02-06 EP disclosed
EP-0937087-A1 PROCESS FOR MAKING MONOHYDROXY-TERMINATED PHOSPHATE COMPOSITIONS Akzo Nobel N.V. (NL) 1999-08-25 EP disclosed
EP-0613902-B1 Process for the manufacture of poly(hydrocarbylene aryl phosphate)compositions AKZO NOBEL NV (NL) 1998-12-09 EP disclosed
US-5817857-A (4-Hydroxy-alkylphenyl diphenyl phosphate flame rerardants AKZO NOBEL NV (NL) 1998-10-06 US disclosed
US-5756797-A REACTING ALKYLENE OXIDE WITH PHOSPHORUS TRICHLORIDE; THEN CHLORINE AND TRIBROMONEOPENTYL ALCOHOL DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-05-26 US disclosed
WO-1998018802-A1 PROCESS FOR MAKING MONOHYDROXY-TERMINATED PHOSPHATE COMPOSITIONS AKZO NOBEL N.V. (NL) 1998-05-07 WO disclosed
US-5728859-A Process for making monohydroxy-terminated phosphate compositions AKZO NOBEL N.V. (NL) 1998-03-17 US disclosed
EP-0808840-A1 Process for preparing tribromoneopentyl chloroalkyl phosphates DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-11-26 EP disclosed
US-5457221-A Process for the manufacture of poly (hydrocarbylene aryl phosphate) compositions AKZO NOBEL N.V. (NL) 1995-10-10 US disclosed
EP-0613902-A1 Process for the manufacture of poly(hydrocarbylene aryl phosphate)compositions Akzo Nobel N.V. (NL) 1994-09-07 EP disclosed
EP-0000132-B1 HALOGEN-SUBSTITUTED ESTERS OF PHOSPHOROUS ACID, POLYMERIC COMPOSITIONS CONTAINING THEM AS REACTIVE FLAME RETARDANTS Velsicol Chemical Corporation (US) 1981-08-05 EP disclosed
US-4281097-A USED IN POLYESTERS AND POLYURETHANES VELSICOL CHEMICAL CORPORATION (US) 1981-07-28 US disclosed
EP-0000132-A1 Halogen-substituted esters of phosphorous acid, polymeric compositions containing them as reactive flame retardants Velsicol Chemical Corporation (US) 1979-01-10 EP disclosed
US-4133846-A FIREPROOFING POLYURETHANES AND POLYESTER VELSICOL CHEMICAL CORPORATION (US) 1979-01-09 US disclosed