Phosphoric Acid

Phosphoric Acid

SCHEMBL6229840

O=P(O)(O)O.O=P(OCCCl)(OCCCl)OCCCl

nearest known ligand 0.83

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.83
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.35
TYMS P04818 1/20 0.30
LPAR3 Q9UBY5 3/20 0.30
LPAR1 Q92633 2/20 0.30
LPAR2 Q9HBW0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26896 0.91 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHR
Methyl Phosphonate SCHEMBL11440398 0.90 ALDH1A1 (0.75) ALDH1A1CYP3A4TSHRLPAR3LPAR1
SCHEMBL499601 0.88 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHR
Hydrochloric Acid SCHEMBL21956045 0.88 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHR
SCHEMBL9749922 0.84 ALDH1A1 (0.75) ALDH1A1CYP3A4TSHR
SCHEMBL11256075 0.83 ALDH1A1 (0.83) ALDH1A1CYP3A4TSHRLPAR3LPAR1
SCHEMBL9298387 0.83 ALDH1A1 (0.83) ALDH1A1CYP3A4TSHR
SCHEMBL30094709 0.83 ALDH1A1 (0.83) ALDH1A1CYP3A4TSHRLPAR3LPAR1
Phosphoric Acid SCHEMBL27536489 0.83 ALDH1A1 (0.57) ALDH1A1LPAR3LPAR1LPAR2
SCHEMBL2688807 0.82 ALDH1A1 (0.64) ALDH1A1CYP3A4LPAR3LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181236-A PPC-based polyurethane composite material and preparation method and application thereof 苏州贝彩纳米科技有限公司 2022-10-14 CN disclosed
US-20140041541-A1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND A METHOD FOR MAKING A PRINTING PLATE KODAK (NEAR EAST) INC. 2014-02-13 US disclosed
EP-2687905-A1 POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARING SAME Eastman Kodak Company (US) 2014-01-22 EP disclosed
US-20050261294-A1 Substituted heteroaryl derivatives, compositions, and methods of use VTVX HOLDINGS I LLC 2005-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261294-A1 Substituted heteroaryl derivatives, compositions, and methods of use MC5R, MC3R, MC4R ALDH1A1 1513/4885CYP3A4 929/4885TSHR 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.