SCHEMBL5850843

SCHEMBL5850843

S=P(Cl)(Oc1ccccc1Br)Oc1ccccc1Br

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.36
LMNA P02545 5/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
KDM4E B2RXH2 2/20 0.33
RAB9A P51151 5/20 0.33
NPC1 O15118 3/20 0.33
HPGD P15428 3/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
GRM4 Q14833 2/20 0.32
ALDH1A1 P00352 3/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
MAPT P10636 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5850849 0.79 HTR7 (0.34) HTR7LMNASMN1; SMN2KDM4ERAB9A
SCHEMBL5850417 0.78 LMNA (0.39) HTR7LMNASMN1; SMN2KDM4ERAB9A
SCHEMBL7801184 0.78 LMNA (0.39) HTR7LMNASMN1; SMN2KDM4ERAB9A
SCHEMBL5851938 0.75 MAPK1 (0.39) LMNASMN1; SMN2HPGDHTTKMT2A
SCHEMBL5850478 0.75 LMNA (0.33) LMNASMN1; SMN2
SCHEMBL9058386 0.75 INPPL1 (0.39) HTR7LMNASMN1; SMN2KDM4ERAB9A
SCHEMBL5851928 0.74 MAPT (0.41) LMNASMN1; SMN2KDM4ERAB9ANPC1
SCHEMBL8016586 0.74 CA1 (0.56) LMNASMN1; SMN2KDM4EHPGDHTT
SCHEMBL29735537 0.73 HTR7 (0.38) HTR7LMNASMN1; SMN2KDM4ERAB9A
SCHEMBL2472741 0.73 HTR7 (0.38) HTR7LMNASMN1; SMN2KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed