Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850860 | 0.87 | HMGCR (0.36) | HMGCRPOLB | |
| SCHEMBL789567 | 0.86 | HMGCR (0.36) | HMGCRPOLBPGK1PGK2NR5A2 | |
| SCHEMBL603636 | 0.78 | ALDH1A1 (0.36) | HMGCRPGK1PGK2NR5A2NR5A1 | |
| SCHEMBL2329995 | 0.77 | CYP3A4 (0.47) | HMGCRPOLBNR5A2NR5A1ALDH1A1 | |
| SCHEMBL2329468 | 0.76 | CYP3A4 (0.46) | HMGCRPOLBNR5A2NR5A1ALDH1A1 | |
| SCHEMBL945588 | 0.76 | CYP3A4 (0.46) | HMGCRPOLBNR5A2NR5A1ALDH1A1 | |
| SCHEMBL31414417 | 0.75 | ALDH1A1 (0.35) | HMGCRPOLBPGK1PGK2NR5A2 | |
| SCHEMBL2334334 | 0.75 | TRPV1 (0.34) | HMGCRALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29108863 | 0.75 | HMGCR (0.41) | HMGCRPGK1PGK2 | |
| SCHEMBL39337 | 0.74 | CYP1A2 (0.34) | POLBCYP1A2CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060219979-A1 | Method of increasing the oxidation stability of biodiesel | DEGUSSA AG (DE) | 2006-10-05 | — | — | US | claimed |
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |