Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 8/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.30 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850864 | 0.86 | HMGCR (0.34) | HMGCRPOLBPGK1PGK2NR5A2 | |
| SCHEMBL603636 | 0.77 | ALDH1A1 (0.36) | HMGCRPGK1PGK2NR5A2NR5A1 | |
| SCHEMBL5850860 | 0.76 | HMGCR (0.36) | HMGCRPOLB | |
| SCHEMBL1859062 | 0.75 | CYP1A2 (0.33) | POLB | |
| SCHEMBL1859057 | 0.74 | POLB (0.34) | POLB | |
| SCHEMBL31414417 | 0.74 | ALDH1A1 (0.35) | HMGCRPOLBPGK1PGK2NR5A2 | |
| SCHEMBL9879682 | 0.73 | POLB (0.41) | POLBALDH1A1 | |
| SCHEMBL28428492 | 0.71 | SRC (0.49) | HMGCRPOLBPGK1PGK2NR5A2 | |
| SCHEMBL7941412 | 0.71 | POLB (0.40) | POLBNR5A2NR5A1ALDH1A1 | |
| SCHEMBL2329995 | 0.70 | CYP3A4 (0.47) | HMGCRPOLBNR5A2NR5A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616473-B1 | MIXTURES CONTAINING PHOSPHOROUS, PROCEDURES FOR THEIR PRODUCTION AND USE | CLARIANT INT LTD (CH) | 2016-11-09 | — | — | EP | disclosed |
| EP-2616473-A2 | PHOSPHORUS-CONTAINING MIXTURES, PROCESSES FOR PREPARING THEM AND USE THEREOF | Clariant Finance (BV) Limited (VG) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034680-A2 | PHOSPHORUS-CONTAINING MIXTURES, PROCESSES FOR PREPARING THEM AND USE THEREOF | CLARIANT INTERNATIONAL LTD (CH) | 2012-03-22 | — | — | WO | disclosed |