Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 9/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.57 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388692 | 0.86 | CYP4Z1 (0.58) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL4866578 | 0.84 | CYP4Z1 (0.53) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL4865106 | 0.83 | CYP4Z1 (0.52) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL2748 | 0.79 | CYP4Z1 (0.50) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL1757403 | 0.79 | CYP4Z1 (0.50) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL9346882 | 0.79 | CYP4Z1 (0.50) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL1757405 | 0.79 | CYP4Z1 (0.50) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL11464650 | 0.79 | CYP4Z1 (0.48) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL14359614 | 0.76 | CYP4Z1 (0.48) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL26617288 | 0.76 | CYP4Z1 (0.48) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115741-B2 | 4-thieno[2,3-D]pyrimidin-4-YL piperazine compounds | ALEXION PHARMACEUTICALS, INC. | 2006-10-03 | — | — | US | disclosed |
| US-20030153556-A1 | Piperazine and homopiperazine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
| WO-2003022214-A2 | PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153556-A1 | Piperazine and homopiperazine compounds | HAMP, MPL, F2 | CYP4Z1 95/4885CYP1A2 54/4885CYP2C8 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.