SCHEMBL585183

SCHEMBL585183

O=C(O)C1c2ccccc2-c2ccc(Cl)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 4/20 0.45
EDNRA P25101 4/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
S100A4 P26447 1/20 0.42
AGTR1 P30556 1/20 0.42
AGTR2 P50052 1/20 0.42
PPIA P62937 2/20 0.40
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
HTR2B P41595 1/20 0.38
CACNB4 O00305 1/20 0.38
CACNA1A O00555 1/20 0.38
CACNA1G O43497 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18385987 0.83 HDAC3 (0.52) EDNRBEDNRAHDAC3HDAC4HDAC7
SCHEMBL40500 0.83 HDAC3 (0.59) EDNRBEDNRAHDAC3HDAC4HDAC7
Benzene SCHEMBL28538497 0.83 HDAC3 (0.59) EDNRBEDNRAHDAC3HDAC4HDAC7
SCHEMBL30001332 0.83 HDAC3 (0.59) EDNRBEDNRAHDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL7052205 0.81 HDAC3 (0.57) EDNRBEDNRAHDAC3HDAC4HDAC7
SCHEMBL1981762 0.81 HDAC3 (0.44) HDAC3HDAC4HDAC7HDAC8HDAC6
SCHEMBL14124766 0.79 EDNRB (0.50) EDNRBEDNRAHDAC3HDAC4HDAC7
SCHEMBL9671710 0.79 HDAC3 (0.44) EDNRBEDNRAHDAC3HDAC4HDAC7
SCHEMBL9449539 0.79 HDAC3 (0.44) EDNRBEDNRAHDAC3HDAC4HDAC7
SCHEMBL1742316 0.79 S100A4 (0.38) EDNRBEDNRAHDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20230292757-A1 SYNERGISTIC AGROCHEMICAL COMPOSITION COMPRISING DIAMIDES AND PLANT GROWTH REGULATORS RAJDHANI PETROCHEMICALS PRIVATE LIMITED (IN) 2023-09-21 US claimed
WO-2022166842-A1 COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF 山东康乔生物科技有限公司 2022-08-11 WO claimed
EP-3407717-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-07-28 EP claimed
EP-3407716-B9 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2021-07-14 EP claimed
EP-3407720-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-03-10 EP claimed
EP-3408263-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-03-03 EP claimed
US-D647068-S1 Light-emitting diode CITIZEN ELECTRONICS CO., LTD. (JP) 2011-10-18 US claimed
WO-2011080044-A2 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2011-07-07 WO claimed
US-20110152077-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-06-23 US claimed
WO-2010116259-A2 PLANT GROWTH REGULATOR ADDITIVE TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2010-10-14 WO claimed
WO-2010081646-A2 FUNGICIDAL ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-07-22 WO claimed
WO-2010081645-A2 FUNGICIDAL ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-07-22 WO claimed
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides BASF SE (DE) 2010-02-11 US claimed
EP-2061320-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2009-05-27 EP claimed
US-20090054237-A1 COMPOSITIONS AND METHODS SYNGENTA CROP PROTECTION, INC. (US) 2009-02-26 US claimed
WO-2008095890-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2008-08-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152077-A1 Active compound combinations BROX, ATL3, AKR7A2 EDNRB 2047/4885EDNRA 3898/4885HDAC3 2246/4885
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides CBR3, CBR1, HCN2 EDNRB 2943/4885EDNRA 2674/4885HDAC3 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.