Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 7/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846713 | 0.88 | POLB (0.41) | SRCBRAFKDRMAPK1PRKCI | |
| SCHEMBL3847147 | 0.83 | FGFR1 (0.39) | FGFR1ALDH1A1MAPTKMT2A | |
| SCHEMBL3849277 | 0.83 | JAK2 (0.35) | KDRFGFR1 | |
| SCHEMBL5852256 | 0.82 | ATM (0.32) | SRCBRAFKDRATMFGFR1 | |
| SCHEMBL3846776 | 0.81 | ATM (0.41) | ATMFGFR1HTTALDH1A1HPGD | |
| SCHEMBL3847832 | 0.80 | QPCT (0.45) | ALDH1A1HPGD | |
| SCHEMBL3845156 | 0.80 | MAPT (0.37) | ATMFGFR1HPGDMAPK1MAPT | |
| SCHEMBL3847278 | 0.78 | RAB9A (0.41) | ALDH1A1HPGDMAPTKMT2ANPSR1 | |
| SCHEMBL3847727 | 0.78 | PIK3CD (0.41) | SRCBRAFKDRALDH1A1HPGD | |
| SCHEMBL3855063 | 0.78 | CYP1A2 (0.38) | SRCBRAFKDRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |