Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853851 | 0.93 | MAPK14 (0.36) | MAPK14BDKRB1CYP3A4 | |
| SCHEMBL3847844 | 0.81 | LTB4R (0.33) | MAPK14ALOX5AP | |
| SCHEMBL3856088 | 0.76 | MAPK14 (0.39) | MAPK14 | |
| SCHEMBL3854592 | 0.73 | FGFR1 (0.35) | — | |
| SCHEMBL3847718 | 0.70 | MAPK14 (0.46) | MAPK14ALOX5AP | |
| SCHEMBL4717283 | 0.69 | KDM2B (0.38) | — | |
| SCHEMBL3853393 | 0.68 | MAPK14 (0.32) | MAPK14 | |
| SCHEMBL5852284 | 0.68 | — | — | |
| SCHEMBL3844886 | 0.68 | MAP4K4 (0.36) | CYP3A4 | |
| SCHEMBL3848408 | 0.68 | TGFBR1 (0.36) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |