SCHEMBL5852345

SCHEMBL5852345

Nc1cc([N+](=O)[O-])ccc1-c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 4/20 0.56
▸ GAA P10253 1/20 0.56
▸ THRB P10828 1/20 0.56
▸ TSHR P16473 1/20 0.56
▸ TDP1 Q9NUW8 5/20 0.55
▸ ALDH1A1 P00352 4/20 0.53
▸ ALOX15 P16050 1/20 0.51
▸ MEN1 O00255 5/20 0.50
▸ KMT2A Q03164 5/20 0.50
▸ MAPT P10636 5/20 0.50
▸ POLB P06746 1/20 0.50
▸ PTPRC P08575 1/20 0.50
▸ S100A4 P26447 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ LMNA P02545 2/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ TLR9 Q9NR96 1/20 0.49
▸ KDM4E B2RXH2 1/20 0.49
▸ MCL1 Q07820 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27911370 0.90 CYP3A4 (0.59) CYP3A4GAATHRBTSHRTDP1
SCHEMBL28104599 0.90 GAA (0.59) CYP3A4GAATHRBTSHRTDP1
SCHEMBL3120559 0.89 RAB9A (0.58) CYP3A4GAATHRBTSHRTDP1
SCHEMBL6011395 0.89 ALDH1A1 (0.59) CYP3A4GAATHRBTSHRTDP1
SCHEMBL28296715 0.88 GAA (0.57) CYP3A4GAATHRBTSHRTDP1
SCHEMBL10487196 0.88 CYP3A4 (0.64) CYP3A4GAATHRBTSHRTDP1
Hydrochloric Acid SCHEMBL6011607 0.87 ALDH1A1 (0.57) CYP3A4GAATHRBTSHRTDP1
SCHEMBL31037362 0.86 CYP19A1 (0.52) CYP3A4GAATHRBTSHRTDP1
SCHEMBL27928945 0.85 CYP3A4 (0.46) CYP3A4GAATHRBTSHRTDP1
SCHEMBL27911360 0.85 CYP3A4 (0.50) CYP3A4GAATHRBTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663437-A 2-(N-benzoylimino)-4, 4-diaminobiphenyl THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1997-09-02 — — US claimed
EP-3965738-B1 METHOD FOR PRODUCTION OF LIPOSOMES UNIV DO MINHO (PT) 2025-08-06 — — EP disclosed
US-20220241203-A1 METHOD FOR PRODUCTION OF LIPOSOMES UNIVERSIDADE DO MINHO (PT) 2022-08-04 — — US disclosed
CN-110426442-B Method for testing nucleic acid gel electrophoresis 苏州优逸兰迪生物科技有限公司 2022-02-11 — — CN disclosed
EP-2366798-B1 Nucleic acid detection process involving energy transfer labels on nucleotide ENZO LIFE SCIENCES INC (US) 2017-06-28 — — EP disclosed
EP-1344835-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2017-06-14 — — EP disclosed
EP-3141615-A1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS Enzo Life Sciences, Inc. (US) 2017-03-15 — — EP disclosed
US-20160281146-A1 OPTIMIZED REAL TIME NUCLEIC ACID DETECTION PROCESSES ENZO LIFE SCIENCES, INC. (US) 2016-09-29 — — US disclosed
US-9068948-B2 Processes for detection of nucleic acids ENZO LIFE SCIENCES, INC. (US) 2015-06-30 — — US disclosed
US-9035057-B2 Dihydroethidine analogues and uses thereof WASHINGTON UNIVERSITY (US) 2015-05-19 — — US disclosed
EP-0641832-B1 Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof DOW CORNING ASIA LTD (JP) 1999-01-13 — — EP disclosed
EP-0628590-B1 Polyimide having organopolysiloxane side chain DOW CORNING (US) 1998-06-03 — — EP disclosed
US-5663437-A 2-(N-benzoylimino)-4, 4-diaminobiphenyl THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1997-09-02 — — US disclosed
US-5663437-A 2-(N-benzoylimino)-4, 4-diaminobiphenyl THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1997-09-02 — — US disclosed
US-5527862-A COMPATIBLE BLENDS; REINFORCED CURED COMPOSITES; HIGH STRENGTH DOW CORNING ASIA, LTD. (JP) 1996-06-18 — — US disclosed
US-5473041-A Increased solubility and low melting points; separation films; diaminobiphenyl-modified polysiloxanes DOW CORNING CORPORATION (US) 1995-12-05 — — US disclosed
EP-0641832-A1 Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof DOW CORNING ASIA, Ltd. (JP) 1995-03-08 — — EP disclosed
EP-0628590-A2 Polyimide having organopolysiloxane side chain DOW CORNING CORPORATION (US) 1994-12-14 — — EP disclosed
US-4670566-A ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS A. H. ROBINS COMPANY, INCORPORATED (US) 1987-06-02 — — US disclosed
US-4440785-A Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation A. H. ROBINS COMPANY, INC. (US) 1984-04-03 — — US disclosed
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