Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5853885 | 0.88 | ITGB1 (0.35) | ITGB1ITGA4LMNAGAA | |
| Hydrochloric Acid SCHEMBL5854332 | 0.83 | KCNK3 (0.36) | LMNAGAA | |
| Hydrochloric Acid SCHEMBL5852836 | 0.81 | PTGS2 (0.36) | LMNA | |
| Hydrochloric Acid SCHEMBL6863878 | 0.80 | POLB (0.35) | LMNAGAA | |
| Hydrochloric Acid SCHEMBL5853163 | 0.78 | NR1H4 (0.41) | LMNAGAA | |
| Hydrochloric Acid SCHEMBL5855430 | 0.78 | TYK2 (0.34) | ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL5853743 | 0.77 | ITGB1 (0.33) | ITGB1ITGA4LMNAGAA | |
| Hydrochloric Acid SCHEMBL5853525 | 0.76 | HPGD (0.40) | GAA | |
| Hydrochloric Acid SCHEMBL5856987 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5856484 | 0.75 | HDAC8 (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |