⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155938 | 0.79 | GAA (0.41) | — | |
| SCHEMBL14351740 | 0.79 | — | — | |
| SCHEMBL10011968 | 0.79 | — | — | |
| SCHEMBL12589075 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL9466291 | 0.78 | GAA (0.44) | — | |
| SCHEMBL10927124 | 0.77 | — | — | |
| SCHEMBL6621890 | 0.77 | — | — | |
| SCHEMBL13854287 | 0.77 | PRKCA (0.32) | — | |
| SCHEMBL18672365 | 0.76 | GAA (0.37) | — | |
| SCHEMBL3163794 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050123835-A1 | Lithium hexafluorophosphate salt, methoxypropionitrile and ethylene carbonate solvents; cobalt lithium oxide cathode, carbon anode; layered separator | POLICELL TECHNOLOGIES, INC. | 2005-06-09 | — | — | US | claimed |
| JP-61100577-A | — | — | None | — | — | JP | disclosed |
| EP-3433250-B1 | HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-08 | — | — | EP | disclosed |
| CN-104470899-B | The 4 isoquinolinol compounds as HIF hydroxylase inhibitors | 菲布罗根有限公司 | 2017-12-26 | — | — | CN | disclosed |
| US-20150283092-A1 | DRUG DELIVERY COMPOSITION | ALKERMES PHARMA IRELAND LTD (IE) | 2015-10-08 | — | — | US | disclosed |
| CN-104470899-A | 4-hydroxy-isoquinoline compounds as HIF hydroxylase inhibitors | FIBROGEN INC | 2015-03-25 | — | — | CN | disclosed |
| EP-2416764-A1 | DRUG DELIVERY COMPOSITION | Alkermes Pharma Ireland Limited (IE) | 2012-02-15 | — | — | EP | disclosed |
| EP-2416782-A1 | CONTROLLED-RELEASE CLOZAPINE COMPOSITIONS | Alkermes Pharma Ireland Limited (IE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010118232-A1 | CONTROLLED-RELEASE CLOZAPINE COMPOSITIONS | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010118228-A1 | DRUG DELIVERY COMPOSITION | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2010-10-14 | — | — | WO | disclosed |
| EP-0169105-B1 | CONTROLLED POROSITY OSMOTIC PUMP | MERCK & CO. INC. (US) | 1991-08-07 | — | — | EP | disclosed |
| US-4968507-A | SUSTAINED RELEASE OF DRUG | MERCK & CO., INC. (US) | 1990-11-06 | — | — | US | disclosed |
| US-4886668-A | CONTROLLED RELEASE OF DILTIAZEM L-MALEATE | MERCK & CO., INC. (US) | 1989-12-12 | — | — | US | disclosed |
| US-4880631-A | DILTIAZEM MALATE WITH SODIUM BITARTRATE BUFFER CORE, POLYMER | MERCK & CO., INC. (US) | 1989-11-14 | — | — | US | disclosed |
| US-4851228-A | Multiparticulate controlled porosity osmotic | MERCK & CO., INC. (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0309051-A1 | Controlled porosity osmotic pump | MERCK & CO. INC. (US) | 1989-03-29 | — | — | EP | disclosed |
| JP-S61100577-A | PRODUCTION OF AMINOFURANONE | SAGAMI CHEM RES CENTER | 1986-05-19 | — | — | JP | disclosed |
| EP-0169105-A2 | Controlled porosity osmotic pump | MERCK & CO. INC. (US) | 1986-01-22 | — | — | EP | disclosed |
| US-4256108-A | Microporous-semipermeable laminated osmotic system | ALZA CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4240961-A | Synthesis of 2-piperazinones and 1,4-diaza-2-keto-cycloheptanes | THE B. F. GOODRICH COMPANY (US) | 1980-12-23 | — | — | US | disclosed |