Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856905 | 0.91 | POLB (0.33) | MEN1KMT2ALMNAPOLBNPC1 | |
| SCHEMBL5853982 | 0.89 | MEN1 (0.33) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL5853370 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL5854465 | 0.86 | HDAC8 (0.38) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL5853551 | 0.83 | KMT2A (0.34) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL5852863 | 0.83 | TAS1R3 (0.36) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL5853877 | 0.81 | HPGD (0.36) | SMN1; SMN2POLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL5854290 | 0.80 | — | — | |
| SCHEMBL5852971 | 0.80 | POLB (0.33) | SMN1; SMN2MEN1KMT2ALMNAPOLB | |
| SCHEMBL5853661 | 0.78 | LMNA (0.32) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |