SCHEMBL5852865

SCHEMBL5852865

C[SiH](C)c1cccc2c1[CH]c1ccccc1-2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5855208 0.78
SCHEMBL28343841 0.72 KDM4E (0.31)
SCHEMBL216981 0.72 ACHE (0.39)
SCHEMBL3064332 0.71 DCUN1D1 (0.40)
SCHEMBL27469812 0.71 ACHE (0.38)
SCHEMBL21722357 0.70 MEN1 (0.33)
SCHEMBL29077885 0.70
SCHEMBL3192100 0.70 ALDH1A1 (0.48)
SCHEMBL1029178 0.69 IDO1 (0.32)
SCHEMBL9462900 0.68 CYP2A6 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0615981-B1 Supported catalyst system, its preparation and its use in olefin polymerisation TARGOR GMBH (DE) 1998-05-06 EP claimed
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-5856414-A USING COORDINATION CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1999-01-05 US disclosed
US-5719095-A FIXING METALLOCENE CATALYST TO SUPPORT BY CONTACT WITH SUPPORTED COCATALYST IN SUSPENSION WHILE IRRADIATING WITH MICROWAVES HOECHST AG (DE) 1998-02-17 US disclosed
EP-0548277-A1 PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM EXXON CHEMICAL PATENTS INC. (US) 1993-06-30 EP disclosed
WO-1992005204-A1 PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM EXXON CHEMICAL PATENTS INC. (US) 1992-04-02 WO disclosed