Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5852870 | 0.99 | SOAT1 (0.44) | SOAT1POLBMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5853770 | 0.99 | SOAT1 (0.44) | SOAT1POLBMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5855392 | 0.96 | NPSR1 (0.39) | SOAT1POLBMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5853837 | 0.91 | NPC1 (0.39) | MEN1KMT2ANPC1RAB9ACYP2C19 | |
| Hydrochloric Acid SCHEMBL5852985 | 0.87 | SOAT1 (0.43) | SOAT1POLBMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5855548 | 0.86 | SOAT1 (0.44) | SOAT1POLBMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5853249 | 0.86 | SOAT1 (0.44) | SOAT1POLBMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5854939 | 0.85 | MAPT (0.36) | POLBMEN1KMT2AGAANPC1 | |
| Hydrochloric Acid SCHEMBL5854750 | 0.83 | NPSR1 (0.39) | SOAT1POLBMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5855504 | 0.80 | LMNA (0.38) | SOAT1POLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |