SCHEMBL5853247

SCHEMBL5853247

Cc1cc(C)n(C(=O)N2CCCCCC2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.49
ALDH1A1 P00352 4/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NPSR1 Q6W5P4 2/20 0.47
ENPP3 O14638 5/20 0.45
ALPL P05186 5/20 0.45
XIAP P98170 5/20 0.45
KDM4E B2RXH2 1/20 0.45
USP2 O75604 1/20 0.45
GAA P10253 1/20 0.45
PKM P14618 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27228823 0.83 ALDH1A1 (0.52) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL12841135 0.82 TSHR (0.46) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL1862337 0.81 TSHR (0.62) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
Cyclohexane SCHEMBL8747257 0.77 TSHR (0.53) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL4457538 0.71 TSHR (0.60) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL3739579 0.71 TSHR (0.60) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL14639865 0.71 TSHR (0.55) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL753657 0.70 TSHR (0.58) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL11561048 0.70 TSHR (0.58) TSHRALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL5329831 0.70 TSHR (0.58) TSHRALDH1A1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022471-B2 Organic silver salt dispersion and production method thereof, photothermographic material and production method thereof KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2006-04-04 US disclosed
US-20050048423-A1 mixing nanostructure particles comprising photostable group IB compounds and photosensitive group IB halides in solvents and binders, to form silver halide emulsions used to form photographic films exhibiting antifogging and high density images KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-03-03 US disclosed
EP-1510858-A1 Organic silver salt dispersion and production method thereof, photothermographic material and production method thereof Konica Minolta Medical & Graphic, Inc. (JP) 2005-03-02 EP disclosed