Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5853348

C[SiH](C)[Zr+2](NC(=O)c1ccccc1)C1=CC=CC1.[Cl-].[Cl-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
IDO1 P14902 1/20 0.35
ALOX15 P16050 1/20 0.35
HDAC1 Q13547 1/20 0.35
CA9 Q16790 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
NCOR2 Q9Y618 1/20 0.35
HTT P42858 1/20 0.35
NPC1 O15118 3/20 0.33
MAPT P10636 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
NFKB1 P19838 2/20 0.33
NFKB2 Q00653 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5853667 0.83 HPGD (0.39) NPC1RAB9ASMN1; SMN2GAAPOLB
Hydrochloric Acid SCHEMBL5855921 0.79
Hydrochloric Acid SCHEMBL5856675 0.75 L3MBTL1 (0.30) L3MBTL1
Hydrochloric Acid SCHEMBL5853301 0.73 TP53 (0.31) HDAC3HDAC1HDAC2HDAC8HDAC6
Hydrochloric Acid SCHEMBL5853515 0.72 NPSR1 (0.34) HDAC8HDAC6RAB9ASMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL5852940 0.71 HPGD (0.31) CA12CA1CA9HTTRAB9A
Hydrochloric Acid SCHEMBL5852765 0.70 HSP90AA1 (0.35) KMT2ALMNAPOLBHPGDMEN1
Hydrochloric Acid SCHEMBL6692607 0.69 HSP90AA1 (0.37) MAPTKMT2ALMNAPOLBMEN1
Hydrochloric Acid SCHEMBL5854169 0.69 HSP90AA1 (0.37) MAPTKMT2ALMNAPOLBMEN1
Hydrochloric Acid SCHEMBL5853101 0.68 KMT2A (0.37) HDAC3CA12CA1IDO1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed