Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5854561 | 0.90 | TAS1R3 (0.39) | KMT2ALMNAMEN1TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL5855021 | 0.87 | KMT2A (0.38) | KMT2ALMNAMEN1TP53TAS1R3 | |
| Hydrochloric Acid SCHEMBL5852810 | 0.86 | MEN1 (0.41) | KMT2ALMNAMEN1TP53TAS1R3 | |
| Hydrochloric Acid SCHEMBL5853072 | 0.82 | HPGD (0.40) | KMT2ALMNAMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5853447 | 0.81 | SMN1; SMN2 (0.46) | KMT2ALMNAMEN1HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL5854943 | 0.80 | KMT2A (0.41) | KMT2ALMNAMEN1ALDH1A1HDAC3 | |
| Hydrochloric Acid SCHEMBL5854729 | 0.79 | KMT2A (0.35) | KMT2ALMNAMEN1PPIAHDAC3 | |
| Hydrochloric Acid SCHEMBL5854099 | 0.79 | KMT2A (0.37) | KMT2ALMNATP53TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL5855206 | 0.78 | POLB (0.40) | KMT2ALMNAMEN1ALDH1A1HDAC3 | |
| Hydrochloric Acid SCHEMBL5852898 | 0.78 | HDAC3 (0.35) | KMT2ALMNAMEN1ALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |