SCHEMBL5853582

SCHEMBL5853582

CC(C)c1ccccc1C(=O)N[Hf](Cl)(Cl)(C1C=Cc2ccccc21)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 2/20 0.31
KCNK9 Q9NPC2 2/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
BCL2 P10415 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5854459 0.91 LMNA (0.33) LMNAKMT2A
SCHEMBL5853411 0.88 KCNK3 (0.33) KCNK3KCNK9LMNAKMT2ABCL2
SCHEMBL5853111 0.87 HPGD (0.36) KCNK3KCNK9KMT2A
SCHEMBL5856051 0.84 ITGB1 (0.31)
SCHEMBL5854316 0.83 ATM (0.32) LMNAKMT2A
SCHEMBL5853704 0.82
SCHEMBL5855377 0.81 TAS1R3 (0.34)
SCHEMBL6859344 0.81 LMNA (0.31) LMNAKMT2A
SCHEMBL6836068 0.81 POLB (0.31)
SCHEMBL5852971 0.80 POLB (0.33) LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed