Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855870 | 0.85 | NPC1 (0.40) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL5855562 | 0.82 | RAB9A (0.49) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL5853729 | 0.81 | NPC1 (0.40) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL5854924 | 0.79 | NPC1 (0.41) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL5853562 | 0.79 | RAB9A (0.41) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL5853227 | 0.78 | NPC1 (0.42) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL5853673 | 0.78 | RAB9A (0.39) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL5854050 | 0.78 | NPC1 (0.37) | NPC1RAB9AHTR7HTR2BDRD2 | |
| SCHEMBL5854884 | 0.77 | PNMT (0.34) | NPC1RAB9APNMT | |
| SCHEMBL5855252 | 0.77 | NPC1 (0.39) | NPC1RAB9ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |