Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARD | Q03181 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854950 | 0.97 | PTPN1 (0.32) | PTPN1HTR2BSIGMAR1TMEM97PPARG | |
| SCHEMBL5853765 | 0.96 | PTPN1 (0.32) | PTPN1HTR2BSIGMAR1TMEM97PPARG | |
| SCHEMBL5856095 | 0.94 | MAOB (0.33) | PTPN1HTR2BSIGMAR1TMEM97PPARG | |
| SCHEMBL5857347 | 0.91 | PTPN1 (0.35) | PTPN1HTR2BSIGMAR1TMEM97PPARG | |
| SCHEMBL7805867 | 0.89 | PPARG (0.33) | PTPN1PPARGPPARDFFAR1 | |
| SCHEMBL5857148 | 0.88 | EGFR (0.33) | PTPN1PPARGPPARDFFAR1 | |
| SCHEMBL5854864 | 0.87 | — | — | |
| SCHEMBL5855298 | 0.85 | NTSR1 (0.30) | — | |
| SCHEMBL6791071 | 0.84 | HTR1A (0.32) | HTR2BSIGMAR1HTR1A | |
| SCHEMBL27560379 | 0.83 | PTPN1 (0.35) | PTPN1HTR2BSIGMAR1TMEM97PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074819-B2 | Benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-07-11 | — | — | US | disclosed |