SCHEMBL5857947

SCHEMBL5857947

C=COC(=O)/C=C\C(=O)OCCC

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.62
ATM Q13315 1/20 0.55
TSHR P16473 6/20 0.47
HPGD P15428 1/20 0.47
MAPT P10636 2/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
APP P05067 1/20 0.41
ALOX5 P09917 1/20 0.41
ALDH1A1 P00352 3/20 0.38
TP53 P04637 2/20 0.38
HIF1A Q16665 2/20 0.38
CYP3A4 P08684 1/20 0.38
HSD17B10 Q99714 1/20 0.38
THRB P10828 1/20 0.36
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28686896 0.94 HCAR2 (0.61) HCAR2ATMTSHRHPGDMAPT
SCHEMBL5857942 0.89 ATM (0.74) HCAR2ATMTSHRHPGDMAPT
SCHEMBL17749669 0.85 HCAR2 (0.67) HCAR2ATMTSHRHPGDMAPT
SCHEMBL322228 0.85 HCAR2 (0.82) HCAR2ATMTSHRHPGDMAPT
SCHEMBL448456 0.85 HCAR2 (0.82) HCAR2ATMTSHRHPGDMAPT
SCHEMBL448454 0.85 HCAR2 (0.82) HCAR2ATMTSHRHPGDMAPT
SCHEMBL11055272 0.83 HCAR2 (0.59) HCAR2ATMMAPTNPSR1ALDH1A1
SCHEMBL5854828 0.83 HCAR2 (0.59) HCAR2ATMMAPTNPSR1ALDH1A1
SCHEMBL11055306 0.83 HCAR2 (0.59) HCAR2ATMMAPTNPSR1ALDH1A1
SCHEMBL4934756 0.83 HCAR2 (0.78) HCAR2ATMTSHRHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6896903-B2 Bioadhesive compositions FIRST WATER LIMITED (GB) 2005-05-24 US claimed
EP-1163309-B1 BIOADHESIVE COMPOSITIONS FIRST WATER LTD (GB) 2004-06-09 EP claimed
US-20020026005-A1 Bioadhesive compositions FIRST WATER LIMITED (GB) 2002-02-28 US claimed
US-20020015689-A1 Bioadhesive compositions FIRST WATER LIMITED (GB) 2002-02-07 US claimed
EP-1163309-A1 BIOADHESIVE COMPOSITIONS First Water Limited (GB) 2001-12-19 EP claimed
EP-1150721-A1 BIOADHESIVE COMPOSITIONS First Water Limited (GB) 2001-11-07 EP claimed
WO-2000046319-A1 BIOADHESIVE COMPOSITIONS FIRST WATER LIMITED (GB) 2000-08-10 WO claimed
WO-2000045864-A1 BIOADHESIVE COMPOSITIONS FIRST WATER LIMITED (GB) 2000-08-10 WO claimed
EP-1026219-A1 Bioadhesive compositions First Water Limited (GB) 2000-08-09 EP claimed
CN-110105679-B Irradiation crosslinking chlorinated polyethylene rubber for LED lamp string and preparation method thereof 中山市新领航塑化科技有限公司 2022-03-15 CN disclosed
US-7152601-B2 Strapless respiratory face mask Barakat, Mohamed Ali (IT) 2006-12-26 US disclosed
EP-1313414-B1 ANTI-SNORING DEVICE COMPRISING A SKIN COMPATIBLE ADHESIVE BARAKAT MOHAMED ALI (BE) 2006-08-23 EP disclosed
EP-1357813-B1 STRAPLESS RESPIRATORY FACE MASK BARAKAT MOHAMED ALI (IT) 2006-06-07 EP disclosed
US-7055526-B2 Anti-snoring device comprising a skin compatible adhesive Bakarat, Mohamed Ali (BE) 2006-06-06 US disclosed
WO-2000045765-A1 DISPOSABLE HUMAN WASTE MANAGEMENT DEVICES WITH IMPROVED ADHESIVE FLANGE THE PROCTER & GAMBLE COMPANY (US) 2000-08-10 WO disclosed
WO-2000045866-A1 DISPOSABLE HUMAN WASTE MANAGEMENT DEVICES WITH ADHESIVE FLANGE THE PROCTER & GAMBLE COMPANY (US) 2000-08-10 WO disclosed
EP-1026219-A1 Bioadhesive compositions First Water Limited (GB) 2000-08-09 EP disclosed
EP-1025824-A1 Disposable human waste management devices with improved adhesive flange THE PROCTER & GAMBLE COMPANY (US) 2000-08-09 EP disclosed
EP-1025867-A1 Disposable human waste management devices with improved adhesive flange to facilitate adhesion in oily conditions THE PROCTER & GAMBLE COMPANY (US) 2000-08-09 EP disclosed
EP-1025865-A1 Disposable absorbent articles with improved adhesive for attachment to the skin to facilitate adhesion in oily conditions THE PROCTER & GAMBLE COMPANY (US) 2000-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020015689-A1 Bioadhesive compositions EPCAM, PHOSPHO1, DSG1 HCAR2 3185/4885ATM 3859/4885TSHR 4376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.