Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.30 |
| ▸ | TUBB | P07437 | 2/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856294 | 0.87 | HTR1A (0.35) | HTR1AHTR2BSIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL5854540 | 0.85 | EDNRB (0.35) | HTR1AHTR2BSIGMAR1MTNR1AALDH1A1 | |
| SCHEMBL5854353 | 0.84 | HTR2B (0.36) | HTR1AHTR2BSIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL5858007 | 0.84 | HTR2B (0.36) | HTR1AHTR2BSIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL7123998 | 0.82 | HTR2B (0.37) | HTR1AHTR2BSIGMAR1MTNR1A | |
| SCHEMBL7129811 | 0.82 | HTR2B (0.36) | HTR1AHTR2BSIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL5854838 | 0.79 | HTR1A (0.33) | HTR1AHTR2BSIGMAR1ALDH1A1 | |
| SCHEMBL5854314 | 0.79 | L3MBTL1 (0.34) | HTR1AHTR2BSIGMAR1 | |
| SCHEMBL5854901 | 0.78 | — | — | |
| SCHEMBL7128090 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074819-B2 | Benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-07-11 | — | — | US | disclosed |
| US-6645951-B1 | Antiestrogens for treating breast cancer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1087959-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | disclosed |