Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5854894 | 0.91 | KMT2A (0.37) | TAS1R3TAS1R1TAS1R2ITGB1 | |
| Hydrochloric Acid SCHEMBL5853525 | 0.88 | HPGD (0.40) | L3MBTL1TYK2 | |
| Hydrochloric Acid SCHEMBL5853650 | 0.86 | SMN1; SMN2 (0.33) | TDP1 | |
| Hydrochloric Acid SCHEMBL5852677 | 0.86 | LMNA (0.34) | ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL5855430 | 0.85 | TYK2 (0.34) | L3MBTL1TAS1R3TAS1R1TAS1R2TYK2 | |
| Hydrochloric Acid SCHEMBL5855617 | 0.84 | NAPRT (0.30) | — | |
| Hydrochloric Acid SCHEMBL5853626 | 0.83 | SMN1; SMN2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL5854430 | 0.82 | POLB (0.36) | TAS1R3TAS1R1TAS1R2 | |
| Hydrochloric Acid SCHEMBL5855109 | 0.81 | GAA (0.33) | — | |
| Hydrochloric Acid SCHEMBL5853885 | 0.81 | ITGB1 (0.35) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |