Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 1.00 |
| ▸ | F10 | P00742 | 1/20 | 0.83 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855519 | 0.91 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5854666 | 0.87 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5855010 | 0.85 | F2 (0.73) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5855598 | 0.78 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7211207 | 0.78 | F2 (0.68) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7379338 | 0.77 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5855530 | 0.76 | F2 (0.75) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL4432108 | 0.75 | F2 (0.77) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7375799 | 0.74 | F2 (0.80) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8366434 | 0.73 | F2 (0.74) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026324-B2 | Thrombin inhibitors | MERCK & CO., INC. (US) | 2006-04-11 | — | — | US | disclosed |
| US-20040097730-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097730-A1 | Thrombin inhibitors | F3, F2, SERPINC1 | F2 2/4885F10 10/4885PRSS1 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.