Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5853386 | 0.88 | NPC1 (0.40) | NPC1RAB9AHTR2BHTR7MAPT | |
| SCHEMBL5853400 | 0.87 | RAB9A (0.51) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL5854944 | 0.84 | RAB9A (0.42) | NPC1RAB9AHTR2BHTR7MAPT | |
| SCHEMBL5853476 | 0.84 | RAB9A (0.42) | NPC1RAB9AHTR2BHTR7MAPT | |
| SCHEMBL5853604 | 0.83 | NPC1 (0.38) | NPC1RAB9AHTR2BHTR7MAPT | |
| SCHEMBL5853840 | 0.83 | NPC1 (0.44) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL5853683 | 0.82 | RAB9A (0.41) | NPC1RAB9AHTR2BHTR7MAPT | |
| SCHEMBL7210057 | 0.82 | NPC1 (0.38) | NPC1RAB9AHTR2BHTR7PNMT | |
| SCHEMBL5854995 | 0.81 | MAPK14 (0.38) | NPC1RAB9ACTSLMEN1KMT2A | |
| SCHEMBL5852745 | 0.81 | NPC1 (0.40) | NPC1RAB9AHTR2BHTR7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |