SCHEMBL585557

SCHEMBL585557

Cc1ccc(N(c2ccc(C)cc2C)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.46
TP53 P04637 2/20 0.46
CYP2A6 P11509 4/20 0.41
CYP1A2 P05177 4/20 0.41
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 2/20 0.39
ADRA2A P08913 1/20 0.39
RAPGEF4 Q8WZA2 3/20 0.38
ACHE P22303 2/20 0.37
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TRPA1 O75762 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30573468 1.00 TDP1 (0.46) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL9097370 0.91 TDP1 (0.39) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL13292333 0.87 CYP1A2 (0.41) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL6351894 0.87 RAPGEF4 (0.39) TDP1TP53ALDH1A1CYP3A4RAPGEF4
SCHEMBL20149501 0.85 ALDH1A1 (0.42) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL7765869 0.85 ALDH1A1 (0.42) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL13826720 0.85 TDP1 (0.39) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL19958559 0.85 ALDH1A1 (0.42) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL19958560 0.84 ALDH1A1 (0.41) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL30829384 0.82 TDP1 (0.41) TDP1TP53CYP2A6CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138669-B1 PROCESS FOR THE PREPARATION OF SILANES FROM METHYLDICHLOROSILANE AND CHLOROSILANES RHONE-POULENC CHIMIE (FR) 1988-08-10 EP claimed
EP-0138670-B1 PROCESS FOR THE PREPARATION OF SILANES WITH A SI-H BOND BY REDISTRIBUTION RHONE-POULENC CHIMIE (FR) 1988-05-25 EP claimed
US-4746752-A QUATERNARY OR TERTIARY AMINE CATALYST RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-05-24 US claimed
US-4605543-A DISTRIBUTION AND DISPROPORTIONATION CATALYSIS RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1986-08-12 US claimed
EP-0138669-A2 Process for the preparation of silanes from methyldichlorosilane and chlorosilanes RHONE-POULENC CHIMIE (FR) 1985-04-24 EP claimed
EP-0138670-A2 Process for the preparation of silanes with a Si-H bond by redistribution RHONE-POULENC CHIMIE (FR) 1985-04-24 EP claimed
US-12416167-B2 Scuff resistant surface coverings TARKETT GDL (LU) 2025-09-16 US disclosed
US-20220363939-A1 One Component UV Curable Compositions And Methods For Making Same DVORCHAK ENTERPRISES LLC (US) 2022-11-17 US disclosed
US-11441048-B2 One component UV curable compositions and methods for making same DVORCHAK ENTERPRISES LLC (US) 2022-09-13 US disclosed
US-20220195739-A1 SCUFF RESISTANT SURFACE COVERINGS TARKETT GDL (LU) 2022-06-23 US disclosed
EP-3972838-A1 SCUFF RESISTANT SURFACE COVERINGS Tarkett GDL (LU) 2022-03-30 EP disclosed
EP-3902664-A1 DECORATIVE WALL OR FLOOR COVERING INSTALLATION METHOD Tarkett GDL (LU) 2021-11-03 EP disclosed
US-11078377-B2 Actinic radiation cured polyurethane coating for decorative surface coverings TARKETT GDL S.A. (LU) 2021-08-03 US disclosed
US-4035321-A Preparation of ultraviolet curable acrylated polymers CELANESE CORPORATION (US) 1977-07-12 US disclosed
US-4016334-A Method of applying high adhesion ultraviolet curable coatings and coated articles CELANESE CORPORATION (US) 1977-04-05 US disclosed
US-4008293-A ACRYLIC COPOLYMER, AMINOPLAST, BINDER PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed
US-3996394-A PHOTOPOLYMERIZATION UNION CARBIDE CORPORATION (US) 1976-12-07 US disclosed
US-3992276-A Unsaturated polyesters for ultraviolet curable coatings CELANESE CORPORATION (US) 1976-11-16 US disclosed
US-3992275-A Low gloss ultraviolet curable coatings utilizing α,α,α-trichlorotoluene as a photoinitiator CELANESE CORPORATION (US) 1976-11-16 US disclosed
US-3966572-A Photocurable low gloss coatings containing silica and acrylic acid UNION CARBIDE CORPORATION (US) 1976-06-29 US disclosed