Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 16/20 | 0.35 |
| ▸ | PPARG | P37231 | 14/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856128 | 0.91 | ESR1 (0.34) | ESR1PPARDPPARGFFAR1CPT1A | |
| SCHEMBL5854837 | 0.90 | ESR1 (0.41) | ESR1PPARDPPARGFFAR1EDNRB | |
| SCHEMBL5856488 | 0.83 | AR (0.33) | PPARDPPARGFFAR1PPARA | |
| SCHEMBL5856257 | 0.82 | FFAR1 (0.31) | PPARDPPARGFFAR1 | |
| SCHEMBL7587424 | 0.81 | ESR1 (0.32) | ESR1PPARDPPARG | |
| SCHEMBL8520859 | 0.80 | PPARG (0.30) | ESR1PPARDPPARG | |
| SCHEMBL6938280 | 0.79 | PPARG (0.32) | ESR1PPARDPPARGFFAR1EDNRB | |
| SCHEMBL6789008 | 0.79 | ESR1 (0.43) | ESR1 | |
| SCHEMBL5854374 | 0.79 | PTPN1 (0.35) | ESR1PPARDPPARGFFAR1PPARA | |
| SCHEMBL5855606 | 0.79 | ESR1 (0.39) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074819-B2 | Benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-07-11 | — | — | US | disclosed |
| US-6645951-B1 | Antiestrogens for treating breast cancer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1087959-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | disclosed |