Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854837 | 0.89 | ESR1 (0.41) | ESR1ESR2HDAC6HDAC1 | |
| SCHEMBL5855606 | 0.85 | ESR1 (0.39) | ESR1ESR2HDAC6HDAC1 | |
| SCHEMBL5854563 | 0.85 | ESR1 (0.40) | ESR1ESR2HDAC6HDAC1 | |
| SCHEMBL5856046 | 0.85 | ESR1 (0.40) | ESR1ESR2HDAC6HDAC1 | |
| SCHEMBL5855904 | 0.85 | ESR1 (0.40) | ESR1ESR2HDAC6HDAC1 | |
| SCHEMBL5854160 | 0.85 | ESR1 (0.38) | ESR1ESR2HDAC6HDAC1 | |
| SCHEMBL5853991 | 0.82 | ESR1 (0.41) | ESR1ESR2HDAC6HDAC1KDM4E | |
| SCHEMBL5856007 | 0.81 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL7587903 | 0.81 | ESR1 (0.48) | ESR1ESR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL7586563 | 0.80 | ESR1 (0.49) | ESR1ESR2HDAC6KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102479-A1 | Novel benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102479-A1 | Novel benzopyran or thiobenzopyran derivatives | NR5A1, SHBG, ESR2 | ESR1 12/4885ESR2 3/4885HDAC6 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.