SCHEMBL5856331

SCHEMBL5856331

C[S+](C)c1ccc(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.43
CA1 P00915 12/20 0.43
JAK2 O60674 1/20 0.37
JAK3 P52333 1/20 0.37
PTK2 Q05397 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
CA9 Q16790 2/20 0.34
AKR1C3 P42330 1/20 0.33
STS P08842 1/20 0.33
KIF11 P52732 1/20 0.32
CXCR2 P25025 1/20 0.31
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5857314 0.98 CA2 (0.44) CA2CA1JAK2JAK3PTK2
SCHEMBL575913 0.86 CA2 (0.51) CA2CA1JAK2JAK3PTK2
SCHEMBL5857817 0.83 CA1 (0.41) CA2CA1JAK2JAK3PTK2
SCHEMBL5856293 0.82 CA2 (0.42) CA2CA1JAK2JAK3PTK2
SCHEMBL31299566 0.81 CA1 (0.48) CA2CA1JAK2JAK3PTK2
SCHEMBL548130 0.81 PIK3CD (0.42) CA2CA1JAK2JAK3PTK2
SCHEMBL5858648 0.81 CXCR2 (0.44) CA2CA1CA9KIF11CXCR2
SCHEMBL5124099 0.81 CA1 (0.46) CA2CA1JAK2JAK3PTK2
SCHEMBL575757 0.80 CA2 (0.46) CA2CA1JAK2JAK3PTK2
SCHEMBL1802710 0.80 CA2 (0.43) CA2CA1JAK2JAK3PTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078148-B2 Photoresist with improved sensitivity and resolution to deep ultraviolet rays/excimer lasers; semiconductors; integrated circuits JSR CORPORATION (JP) 2006-07-18 US disclosed
US-20040072094-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2004-04-15 US disclosed