⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045014 | 0.73 | — | — | |
| SCHEMBL8121239 | 0.71 | — | — | |
| SCHEMBL2050390 | 0.63 | — | — | |
| SCHEMBL7350093 | 0.62 | — | — | |
| SCHEMBL11985519 | 0.61 | — | — | |
| SCHEMBL3122958 | 0.60 | — | — | |
| SCHEMBL6210725 | 0.59 | — | — | |
| SCHEMBL819715 | 0.58 | — | — | |
| SCHEMBL6097249 | 0.57 | — | — | |
| SCHEMBL6645893 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684700-A | Silyl substituted pyrroloindole derivative and synthetic method and application thereof | 赣南医科大学 | 2024-09-24 | — | — | CN | claimed |
| EP-4147283-A1 | LAYER SYSTEM FOR AN ORGANIC ELECTRONIC COMPONENT | Heliatek GmbH (DE) | 2023-03-15 | — | — | EP | claimed |
| US-11542481-B2 | Morphinan N-demethylase isolated from the methylobacterium thebainfresser and methods of use thereof | DONALD DANFORTH PLANT SCIENCE CENTER (US) | 2023-01-03 | — | — | US | claimed |
| WO-2021223814-A1 | LAYER SYSTEM FOR AN ORGANIC ELECTRONIC COMPONENT | HELIATEK GMBH (DE) | 2021-11-11 | — | — | WO | claimed |
| CN-112724151-A | Pyrroloindole compound and preparation method and application thereof | 闫仲芬 | 2021-04-30 | — | — | CN | claimed |
| US-10950811-B2 | Optoelectronic component | HELIATEK GMBH (DE) | 2021-03-16 | — | — | US | claimed |
| CN-109180691-B | C3-aromatic pyrroloindole alkaloid and synthetic method thereof | 武汉大学 | 2020-07-10 | — | — | CN | claimed |
| CN-107868087-B | Method for preparing pyrroloindole derivatives | 浙江大学 | 2020-03-24 | — | — | CN | claimed |
| US-20190352618-A1 | MORPHINAN N-DEMETHYLASE ISOLATED FROM THE METHYLOBACTERIUM THEBAINFRESSER AND METHODS OF USE THEREOF | DONALD DANFORTH PLANT SCIENCE CENTER | 2019-11-21 | — | — | US | claimed |
| WO-2018136654-A1 | MORPHINAN N-DEMETHYLASE ISOLATED FROM THE METHYLOBACTERIUM THEBAINFRESSER AND METHODS OF USE THEREOF | DONALD DANFORTH PLANT SCIENCE CENTER (US) | 2018-07-26 | — | — | WO | claimed |
| EP-1505971-A2 | ADMINISTRATION OF ACETYLCHOLINESTERASE INHIBITORS TO THE CEREBRAL SPINAL FLUID | Nastech Pharmaceutical Company Inc. (US) | 2005-02-16 | — | — | EP | claimed |
| EP-0972775-B1 | PYRROLOINDOLE DERIVATIVES AND INTERMEDIATES IN PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-12-08 | — | — | EP | claimed |
| WO-2004002402-A2 | ADMINISTRATION OF ACETYLCHOLINESTERASE INHIBITORS TO THE CEREBRAL SPINAL FLUID | NASTECH PHARMACEUTICAL COMPANY INC. (US) | 2004-01-08 | — | — | WO | claimed |
| US-20030225031-A1 | Administration of acetylcholinesterase inhibitors to the cerebral spinal fluid | NASTECH PHARMACEUTICAL COMPANY INC. | 2003-12-04 | — | — | US | claimed |
| EP-0937726-B1 | INTERMEDIATES FOR THE PREPARATION OF DUOCARMYCIN SA AND DERIVATIVES THEREOF, AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | KYORIN SEIYAKU KK (JP) | 2003-03-12 | — | — | EP | claimed |
| US-6492346-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | claimed |
| US-6080859-A | 1-CHLOROMETHYL, 3-((HETEROARYL OR ARYL)CARBONYL), 5-(HETEROCYCLE-AMINOCARBONYLOXY),7-TRIFLUOROMETHYL, 8-ALKOXYCARBONYL-1,2,3,6-TETRAHYDROPYRROLO(3,2-E)INDOLE OF GIVEN STRUCTURE; ANTITUMOR AND ANTIMICROBIAL ACTIVITY | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-06-27 | — | — | US | claimed |
| US-6066742-A | Intermediates for the preparation of duocarmycin SA and derivatives thereof, and process for the production of the intermediates | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-05-23 | — | — | US | claimed |
| EP-0972775-A1 | PYRROLOINDOLE DERIVATIVES AND INTERMEDIATES IN PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-01-19 | — | — | EP | claimed |
| EP-0937726-A1 | INTERMEDIATES FOR THE PREPARATION OF DUOCARMYCIN SA AND DERIVATIVES THEREOF, AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-08-25 | — | — | EP | claimed |