Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | ACP1 | P24666 | 4/20 | 0.38 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586670 | 0.85 | AVPR2 (0.40) | SLC6A2SLC6A4AVPR2AVPR1ANPY1R | |
| SCHEMBL2675874 | 0.79 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ACP1CTSS | |
| SCHEMBL6644033 | 0.72 | GAA (0.47) | SLC6A4ACP1QPCT | |
| SCHEMBL585198 | 0.71 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6586566 | 0.70 | TSHR (0.51) | — | |
| SCHEMBL29038446 | 0.69 | FDPS (0.52) | — | |
| SCHEMBL633762 | 0.68 | KCNH2 (0.43) | — | |
| SCHEMBL586415 | 0.68 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL585767 | 0.68 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL586043 | 0.68 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417124-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | Eli Lilly and Company (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117979-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | ELI LILLY AND COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |