Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 11/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585768 | 0.85 | SLC6A2 (0.52) | AVPR2AVPR1ANPY1RSLC6A2SLC6A4 | |
| SCHEMBL2676100 | 0.78 | SLC6A2 (0.33) | SLC6A2SLC6A4SSTR4 | |
| SCHEMBL7410443 | 0.71 | CHRNB2 (0.56) | — | |
| Hydrochloric Acid SCHEMBL7415122 | 0.70 | CHRNB2 (0.55) | — | |
| SCHEMBL997318 | 0.70 | ITGB3 (0.42) | NPY1RSLC6A2SLC6A4 | |
| SCHEMBL586304 | 0.69 | SLC6A2 (0.55) | SLC6A2SLC6A4 | |
| SCHEMBL935709 | 0.68 | NPY1R (0.50) | NPY1RSLC6A2SLC6A4 | |
| SCHEMBL935234 | 0.68 | NPY1R (0.50) | NPY1RSLC6A2SLC6A4 | |
| SCHEMBL2675321 | 0.68 | SLC6A2 (0.48) | SLC6A2SLC6A4 | |
| SCHEMBL30670081 | 0.68 | AVPR2 (0.42) | AVPR2AVPR1ANPY1RSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417124-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | Eli Lilly and Company (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117979-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | ELI LILLY AND COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |