Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12221369 | 0.93 | MAPT (0.34) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL11639183 | 0.91 | MAPT (0.33) | TSHRALDH1A1MAPT | |
| SCHEMBL1600712 | 0.85 | — | — | |
| SCHEMBL11019771 | 0.83 | TSHR (0.30) | TSHR | |
| SCHEMBL335028 | 0.78 | — | — | |
| SCHEMBL15134445 | 0.76 | POLB (0.33) | ALDH1A1TDP1 | |
| SCHEMBL17931785 | 0.76 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL2462839 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11018931 | 0.76 | PRKD3 (0.37) | — | |
| SCHEMBL7025332 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080530-B1 | HYDRAULIC FLUIDS CONTAINING CYANO DERIVATIVES OF CYCLIC KETALS AND ACETALS | THE DOW CHEMICAL COMPANY (US) | 1985-08-28 | — | — | EP | claimed |
| EP-0080530-A1 | Hydraulic fluids containing cyano derivatives of cyclic ketals and acetals | THE DOW CHEMICAL COMPANY (US) | 1983-06-08 | — | — | EP | claimed |
| US-4320024-A | Hydraulic fluids containing cyano derivatives of cyclic ketals and acetals | THE DOW CHEMICAL COMPANY (US) | 1982-03-16 | — | — | US | claimed |
| US-8513162-B2 | Halogen-containing organosulfur compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20110257226-A1 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-20 | — | — | US | disclosed |
| US-7919523-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-7919523-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20090042973-A1 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED | 2009-02-12 | — | — | US | disclosed |
| US-20090042973-A1 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED | 2009-02-12 | — | — | US | disclosed |
| US-7442718-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442718-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-28 | — | — | US | disclosed |
| WO-2000000490-A2 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |
| WO-2000000487-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |
| US-5874427-A | MIGRAINE | ELI LILLY AND COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1998046570-A1 | SUBSTITUTED HETEROAROMATIC 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0080530-B1 | HYDRAULIC FLUIDS CONTAINING CYANO DERIVATIVES OF CYCLIC KETALS AND ACETALS | THE DOW CHEMICAL COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4501679-A | WATER OR ACID SCAVENGERS | THE DOW CHEMICAL COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0080530-A1 | Hydraulic fluids containing cyano derivatives of cyclic ketals and acetals | THE DOW CHEMICAL COMPANY (US) | 1983-06-08 | — | — | EP | disclosed |
| US-4320024-A | Hydraulic fluids containing cyano derivatives of cyclic ketals and acetals | THE DOW CHEMICAL COMPANY (US) | 1982-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042973-A1 | Inhibitors of aspartyl protease | SPINT2, DNPEP, PRSS1 | TSHR 4851/4885ALDH1A1 1604/4885TDP1 722/4885 |
| US-20110257226-A1 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF | C1S, C5, L3MBTL3 | TSHR 70/4885ALDH1A1 1174/4885TDP1 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.