⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521340 | 1.00 | — | — | |
| SCHEMBL1735586 | 1.00 | — | — | |
| Bicarbonate SCHEMBL4300889 | 0.83 | — | — | |
| Phosphoric Acid SCHEMBL16110763 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL137154 | 0.75 | — | — | |
| SCHEMBL483199 | 0.75 | — | — | |
| SCHEMBL102759 | 0.75 | — | — | |
| SCHEMBL16933800 | 0.72 | — | — | |
| SCHEMBL8285979 | 0.70 | — | — | |
| SCHEMBL8431701 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102147-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2026-05-15 | — | — | WO | disclosed |
| WO-2025101575-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-X L DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |
| US-20150047664-A1 | COSMETIC PROCESS FOR CARING FOR AND/OR MAKING UP KERATIN MATERIALS | L'OREAL (FR) | 2015-02-19 | — | — | US | disclosed |
| EP-2830572-A1 | COSMETIC PROCESS FOR CARING FOR AND/OR MAKING UP KERATIN MATERIALS | L'OREAL (FR) | 2015-02-04 | — | — | EP | disclosed |
| WO-2013144871-A1 | COSMETIC PROCESS FOR CARING FOR AND/OR MAKING UP KERATIN MATERIALS | L'OREAL (FR) | 2013-10-03 | — | — | WO | disclosed |
| US-7847105-B2 | Methods and compounds for preparing CC-1065 analogs | MEDAREX, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-20080281102-A1 | Methods and Compounds For Preparing Cc-1065 Analogs | MEDAREX, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| US-7150765-B2 | Fatty acid-free liquid dye composition comprising at least one oxidation base and 2-methyl-1, 3-propanediol, dyeing process, and device | L'OREAL S.A. (FR) | 2006-12-19 | — | — | US | disclosed |
| US-20050050649-A1 | Fatty acid-free liquid dye composition comprising at least one oxidation base and 2-methyl-1,3-propanediol, dyeing process, and device | L'OREAL S.A. (FR) | 2005-03-10 | — | — | US | disclosed |
| EP-0271240-A2 | Fluorobenzyl esters | ZENECA LIMITED (GB) | 1988-06-15 | — | — | EP | disclosed |
| US-3952100-A | PHOSPHORODITHIOLATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | disclosed |