Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6907349 | 0.76 | BRD4 (0.30) | — | |
| Hydrochloric Acid SCHEMBL8856044 | 0.69 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7160430 | 0.68 | MEN1 (0.33) | MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL5858086 | 0.67 | MEN1 (0.32) | MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL6905921 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL887662 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL8380884 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL4457339 | 0.63 | BRD4 (0.37) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3681484 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL3681482 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6641925-B1 | Metallocene system catalyzed cycloolefin copolymer laminated to polyvinyl chloride; extrusion coated film as packaging | TICONA GMBH (DE) | 2003-11-04 | — | — | US | claimed |
| US-7026401-B1 | Method of producing amorphous polyolefins with a wide mole weight distribution | TICONA GMBH (DE) | 2006-04-11 | — | — | US | disclosed |
| US-6927184-B1 | Method of producing microfiber nonwovens that contain cycloolefin polymers | TICONA GMBH (DE) | 2005-08-09 | — | — | US | disclosed |
| EP-1364777-B1 | Multi-layer laminate, packaging material and packages made therefrom | TICONA GMBH (DE) | 2005-08-03 | — | — | EP | disclosed |
| US-6921563-B2 | Multi-layer laminate, packaging material and packages made therefrom | TICONA GMBH (DE) | 2005-07-26 | — | — | US | disclosed |
| US-6844059-B2 | Long-fiber-reinforced polyolefin structure, process for its production, and moldings produced therefrom | TICONA GMBH (DE) | 2005-01-18 | — | — | US | disclosed |
| US-6818590-B2 | TO ELIMINATE CONTAMINANTS OF SOIL OR WATERS | TICONA GMBH (DE) | 2004-11-16 | — | — | US | disclosed |
| US-6767966-B2 | BIAXIALLY ORIENTED FILMS, BLISTER PACKS, OR MIXTURES WITH OTHER PLASTICS; INJECTION OR BLOW MOLDING; SHRINKAGE INHIBITION | TICONA GMBH (DE) | 2004-07-27 | — | — | US | disclosed |
| US-6762265-B1 | RING RETENTION FREE RADICAL COPOLYMERIZATION OF POLYCYCLIC, MONOCYLIC AND ALIPHATIC MONOMERS | TICONA GMBH (DE) | 2004-07-13 | — | — | US | disclosed |
| EP-1364777-A1 | Multi-layer laminate, packaging material and packages made therefrom | Ticona GmbH (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-6383396-B1 | USING CYCLOOLEFIN COPOLYMER | TICONA GMBH (DE) | 2002-05-07 | — | — | US | disclosed |
| US-20020012781-A1 | MONO-OR MULTILAYER FILM | TICONA GMBH (DE) | 2002-01-31 | — | — | US | disclosed |
| US-6329047-B1 | CYCLOOLEFIN COPOLYMER FILM, POLYVINYLIDENE CHLORIDE, LAMINATION TO FILM | TICONA GMBH (DE) | 2001-12-11 | — | — | US | disclosed |
| US-6239187-B1 | 0.1-100% OF POLYMERIZED UNITS DERIVED FROM ONE OR MORE POLYCYCLIC OLEFINS HAVING ONE OR MORE NORBORNENE UNITS AND 0-99% OF POLYMERIZED UNITS DERIVED FROM ONE OR MORE ACYCLIC OLEFINS | TICONA GMBH (DE) | 2001-05-29 | — | — | US | disclosed |
| US-6132622-A | FILTRATION THROUGH DEVICE CONTAINING CYCLOOLEFIN COPOLYMER WITH ACYCLIC UNSATURATED MONOMER | TICONA GMBH (DE) | 2000-10-17 | — | — | US | disclosed |
| US-6008298-A | BLENDS OF CYCLOOLEFIN COPOLYMERS WITH CORE/SHELL PARTICLES HAVING DIAMETER OF 0.01 TO 0.7 MICROMETERS; IMPROVED ELONGATION AT BREAK, FLEXURAL STRENGTH AND IMPACT STRENGTH | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-28 | — | — | US | disclosed |
| US-5866662-A | HAS AT ONE OR BOTH ENDS AN OLEFINICALLY UNSATURATED GROUP HAVING AT LEAST 3 CARBON ATOMS. | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |
| US-5863986-A | ETHYLENE WITH NORBORNENE OR TETRACYCLODODECENE IN A BLEND FOR CORE SHELL POLYMERS | TICONA GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5856414-A | USING COORDINATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |
| US-5610253-A | Cycloolefin polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |