Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160430 | 0.99 | MEN1 (0.33) | MEN1KMT2AATM | |
| SCHEMBL28310710 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL6907352 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27432494 | 0.74 | — | — | |
| SCHEMBL7719822 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9010073 | 0.74 | — | — | |
| Ethane SCHEMBL8635840 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7066944 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7068019 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL9010257 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6641925-B1 | Metallocene system catalyzed cycloolefin copolymer laminated to polyvinyl chloride; extrusion coated film as packaging | TICONA GMBH (DE) | 2003-11-04 | — | — | US | claimed |
| US-7026401-B1 | Method of producing amorphous polyolefins with a wide mole weight distribution | TICONA GMBH (DE) | 2006-04-11 | — | — | US | disclosed |
| US-6927184-B1 | Method of producing microfiber nonwovens that contain cycloolefin polymers | TICONA GMBH (DE) | 2005-08-09 | — | — | US | disclosed |
| EP-1364777-B1 | Multi-layer laminate, packaging material and packages made therefrom | TICONA GMBH (DE) | 2005-08-03 | — | — | EP | disclosed |
| US-6921563-B2 | Multi-layer laminate, packaging material and packages made therefrom | TICONA GMBH (DE) | 2005-07-26 | — | — | US | disclosed |
| US-6844059-B2 | Long-fiber-reinforced polyolefin structure, process for its production, and moldings produced therefrom | TICONA GMBH (DE) | 2005-01-18 | — | — | US | disclosed |
| US-6818590-B2 | TO ELIMINATE CONTAMINANTS OF SOIL OR WATERS | TICONA GMBH (DE) | 2004-11-16 | — | — | US | disclosed |
| US-6767966-B2 | BIAXIALLY ORIENTED FILMS, BLISTER PACKS, OR MIXTURES WITH OTHER PLASTICS; INJECTION OR BLOW MOLDING; SHRINKAGE INHIBITION | TICONA GMBH (DE) | 2004-07-27 | — | — | US | disclosed |
| US-6762265-B1 | RING RETENTION FREE RADICAL COPOLYMERIZATION OF POLYCYCLIC, MONOCYLIC AND ALIPHATIC MONOMERS | TICONA GMBH (DE) | 2004-07-13 | — | — | US | disclosed |
| EP-1364777-A1 | Multi-layer laminate, packaging material and packages made therefrom | Ticona GmbH (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-6383396-B1 | USING CYCLOOLEFIN COPOLYMER | TICONA GMBH (DE) | 2002-05-07 | — | — | US | disclosed |
| US-20020012781-A1 | MONO-OR MULTILAYER FILM | TICONA GMBH (DE) | 2002-01-31 | — | — | US | disclosed |
| US-6329047-B1 | CYCLOOLEFIN COPOLYMER FILM, POLYVINYLIDENE CHLORIDE, LAMINATION TO FILM | TICONA GMBH (DE) | 2001-12-11 | — | — | US | disclosed |
| US-6239187-B1 | 0.1-100% OF POLYMERIZED UNITS DERIVED FROM ONE OR MORE POLYCYCLIC OLEFINS HAVING ONE OR MORE NORBORNENE UNITS AND 0-99% OF POLYMERIZED UNITS DERIVED FROM ONE OR MORE ACYCLIC OLEFINS | TICONA GMBH (DE) | 2001-05-29 | — | — | US | disclosed |
| US-6132622-A | FILTRATION THROUGH DEVICE CONTAINING CYCLOOLEFIN COPOLYMER WITH ACYCLIC UNSATURATED MONOMER | TICONA GMBH (DE) | 2000-10-17 | — | — | US | disclosed |
| US-6008298-A | BLENDS OF CYCLOOLEFIN COPOLYMERS WITH CORE/SHELL PARTICLES HAVING DIAMETER OF 0.01 TO 0.7 MICROMETERS; IMPROVED ELONGATION AT BREAK, FLEXURAL STRENGTH AND IMPACT STRENGTH | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-28 | — | — | US | disclosed |
| US-5866662-A | HAS AT ONE OR BOTH ENDS AN OLEFINICALLY UNSATURATED GROUP HAVING AT LEAST 3 CARBON ATOMS. | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |
| US-5863986-A | ETHYLENE WITH NORBORNENE OR TETRACYCLODODECENE IN A BLEND FOR CORE SHELL POLYMERS | TICONA GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5856414-A | USING COORDINATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |
| US-5610253-A | Cycloolefin polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |