SCHEMBL5859010

SCHEMBL5859010

OCCCCN1CCSCC1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.40
HRH3 Q9Y5N1 1/20 0.39
ARG1 P05089 1/20 0.36
ARG2 P78540 1/20 0.36
GAA P10253 1/20 0.34
FAAH O00519 1/20 0.33
PHGDH O43175 1/20 0.33
MGLL Q99685 1/20 0.33
PNMT P11086 1/20 0.33
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
SIGMAR1 Q99720 1/20 0.32
PAOX Q6QHF9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12936745 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL12936758 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL5857741 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL12936756 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL5857565 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL12936760 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL12936751 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL12936748 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL12936743 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA
SCHEMBL12936744 0.98 HRH3 (0.42) KDM1AHRH3ARG1ARG2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846294-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-30 US disclosed
US-8846294-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-30 US disclosed
CN-103429607-A C-17 and C-3 modified triterpenoids with HIV maturation inhibitory activity BRISTOL MYERS SQUIBB CO 2013-12-04 CN disclosed
US-20120251946-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
US-20120251946-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
US-7112594-B2 Fused bicyclic amide compounds and medicinal use thereof MITSUBISHI PHARMA CORPORATION (JP) 2006-09-26 US disclosed
US-7015218-B1 Amide compounds and medicinal use thereof MITSUBISHI PHARMA CORPORATION (JP) 2006-03-21 US disclosed
EP-1176140-B1 AMIDE COMPOUNDS AND MEDICINAL USE THEREOF MITSUBISHI PHARMA CORP (JP) 2004-12-29 EP disclosed
US-20030203909-A1 Fused bicyclic amide compounds and medicinal use thereof MITSUBISHI PHARMA CORPORATION (JP) 2003-10-30 US disclosed
EP-1310488-A1 FUSED BICYCLIC AMIDE COMPOUNDS AND MEDICINAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2003-05-14 EP disclosed
EP-0783490-B1 1-ACYL-4-ALIPHATIC AMINOPIPERIDINE COMPOUNDS NOVARTIS AG (CH) 2002-02-06 EP disclosed
EP-1176140-A1 AMIDE COMPOUNDS AND MEDICINAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2002-01-30 EP disclosed
US-5935951-A ANTAGONIST AGAINST SUBSTANCE P NOVARTIS FINANCE CORPORATION (US) 1999-08-10 US disclosed
EP-0783490-A1 1-ACYL-4-ALIPHATYLAMINOPIPERIDINE COMPOUNDS Novartis AG (CH) 1997-07-16 EP disclosed
WO-1996010562-A1 1-ACYL-4-ALIPHATYLAMINOPIPERIDINE COMPOUNDS NOVARTIS AG (CH) 1996-04-11 WO disclosed
CN-1091288-A The oxytocin antagonist OTSUKA PHARMA CO LTD (JP) 1994-08-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030203909-A1 Fused bicyclic amide compounds and medicinal use thereof BET1, NFATC1, ARG1 KDM1A 179/4885HRH3 38/4885ARG1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.