SCHEMBL585941

SCHEMBL585941

CCC/C(=C(\C)C(=O)O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.53
CES1 P23141 6/20 0.53
ESR1 P03372 3/20 0.51
PTGS2 P35354 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
HPGD P15428 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.43
ALOX5 P09917 1/20 0.41
TP53 P04637 1/20 0.41
ESR2 Q92731 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1792697 1.00 CES2 (0.53) CES2CES1ESR1PTGS2SMN1; SMN2
SCHEMBL5863245 1.00 CES2 (0.53) CES2CES1ESR1PTGS2SMN1; SMN2
SCHEMBL3725995 0.89 PTGS2 (0.62) CES2CES1ESR1PTGS2
SCHEMBL3725992 0.89 PTGS2 (0.62) CES2CES1ESR1PTGS2
SCHEMBL8156308 0.89 PTGS2 (0.62) CES2CES1ESR1PTGS2
SCHEMBL6473817 0.86 CES2 (0.58) CES2CES1ESR1PTGS2
SCHEMBL6255793 0.86 CES2 (0.58) CES2CES1ESR1PTGS2
SCHEMBL238653 0.86 CES2 (0.58) CES2CES1ESR1PTGS2
SCHEMBL343138 0.86 CES2 (0.58) CES2CES1ESR1PTGS2
SCHEMBL343140 0.86 CES2 (0.58) CES2CES1ESR1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2072083-B1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma SYMRISE AG (DE) 2012-02-15 EP claimed
EP-2072083-A1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma Symrise GmbH & Co. KG (DE) 2009-06-24 EP claimed
EP-1682230-A1 4,8-DIMETHYL-7-NONEN-2-ONE AND 4,8-DIMETHYLNONAN-2-ONE USED AS PERFUMES Symrise GmbH & Co. KG (DE) 2006-07-26 EP claimed
WO-2005004825-A1 4,8-DIMETHYL-7-NONEN-2-ONE AND 4,8-DIMETHYLNONAN-2-ONE USED AS PERFUMES SYMRISE GMBH & CO. KG (DE) 2005-01-20 WO claimed
EP-2072083-B1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma SYMRISE AG (DE) 2012-02-15 EP disclosed
EP-2072083-A1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma Symrise GmbH & Co. KG (DE) 2009-06-24 EP disclosed
EP-1682230-A1 4,8-DIMETHYL-7-NONEN-2-ONE AND 4,8-DIMETHYLNONAN-2-ONE USED AS PERFUMES Symrise GmbH & Co. KG (DE) 2006-07-26 EP disclosed
WO-2005004825-A1 4,8-DIMETHYL-7-NONEN-2-ONE AND 4,8-DIMETHYLNONAN-2-ONE USED AS PERFUMES SYMRISE GMBH & CO. KG (DE) 2005-01-20 WO disclosed
EP-0718326-B1 Plastic particles with improved thermostability ROEHM GMBH (DE) 1998-06-03 EP disclosed
EP-0718326-A1 Plastic particles with improved thermostability Röhm GmbH (DE) 1996-06-26 EP disclosed