SCHEMBL585948

SCHEMBL585948

C=C(CCOCCO)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
MAPK1 P28482 1/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.33
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9062589 0.98 MEN1 (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL8815476 0.91 TSHR (0.46) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL9436946 0.91 TET2 (0.37) TSHRALDH1A1TET2TET3TET1
SCHEMBL8355965 0.88 TET2 (0.36) TSHRMEN1KMT2AALDH1A1TET2
SCHEMBL11124813 0.88 TET2 (0.36) TSHRMEN1KMT2AALDH1A1TET2
Di(Hydroxyethyl)Ether SCHEMBL6990322 0.87 TSHR (0.42) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL1874982 0.87 TSHR (0.42) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL8966786 0.85 MEN1 (0.44) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL2796019 0.85 MEN1 (0.44) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL28322244 0.84 GAA (0.49) TSHRMEN1KMT2AALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069172-A1 DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR ROCHE DIABETES CARE INC (US) 2026-03-12 US claimed
EP-3578588-B1 HIGH EFFICIENCY WET STRENGTH RESINS FROM NEW CROSS-LINKERS ECOLAB USA INC (US) 2025-07-02 EP claimed
EP-3787509-B1 IMPROVED DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR HOFFMANN LA ROCHE (CH) 2022-06-22 EP claimed
EP-3787509-A1 IMPROVED DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR F. Hoffmann-La Roche AG (CH) 2021-03-10 EP claimed
US-20210045664-A1 DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR ROCHE DIABETES CARE, INC. 2021-02-18 US claimed
EP-2875064-B1 HIGH EFFICIENCY WET STRENGTH RESINS FROM NEW CROSS-LINKERS ECOLAB USA INC (US) 2019-06-26 EP claimed
EP-2052051-B1 SUBTERRANEAN TREATMENT FLUIDS, FRICTION REDUCING COPOLYMERS, AND ASSOCIATED METHODS HALLIBURTON ENERGY SERV INC (US) 2012-02-15 EP claimed
EP-0562861-B1 Optical materials with a high refractive index and method for producing the same MITSUBISHI CHEM CORP (JP) 1996-05-29 EP claimed
EP-0474452-B1 Thermal transfer dye image receiving sheet NEW OJI PAPER CO LTD (JP) 1995-07-12 EP claimed
US-20260069172-A1 DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR ROCHE DIABETES CARE INC (US) 2026-03-12 US disclosed
US-12446802-B2 Diffusion layer for an enzymatic in-vivo sensor ROCHE DIABETES CARE, INC. (US) 2025-10-21 US disclosed
EP-3787509-B1 IMPROVED DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR HOFFMANN LA ROCHE (CH) 2022-06-22 EP disclosed
EP-3787509-A1 IMPROVED DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR F. Hoffmann-La Roche AG (CH) 2021-03-10 EP disclosed
US-20210045664-A1 DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR ROCHE DIABETES CARE, INC. 2021-02-18 US disclosed
EP-0894504-A2 Bioactive coating with low friction surface HÜLS AKTIENGESELLSCHAFT (DE) 1999-02-03 EP disclosed
EP-0893164-A2 Bioactive coating of surfaces using crosslinking agents HÜLS AKTIENGESELLSCHAFT (DE) 1999-01-27 EP disclosed
EP-0879607-A2 Method and reducing friction of hydrophilic surfaces HÜLS AKTIENGESELLSCHAFT (DE) 1998-11-25 EP disclosed
EP-0860213-A2 Bioactive coating on surfaces HÜLS AKTIENGESELLSCHAFT (DE) 1998-08-26 EP disclosed
EP-0852952-A2 Bioactive coating of surfaces HÜLS AKTIENGESELLSCHAFT (DE) 1998-07-15 EP disclosed
EP-0852238-A2 Polymers with bacteriophobe and optionally cell proliferation inhibitant properties HÜLS AKTIENGESELLSCHAFT (DE) 1998-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069172-A1 DIFFUSION LAYER FOR AN ENZYMATIC IN-VIVO SENSOR LDHA, LDHB, BTD TSHR 1286/4885MAPK1 1864/4885MEN1 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.