SCHEMBL585949

SCHEMBL585949

Cc1ccc(CNC(=O)O)cc1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 2/20 0.58
NPC1 O15118 1/20 0.49
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
HTT P42858 1/20 0.48
TSHR P16473 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
RAB9A P51151 1/20 0.46
MMP13 P45452 1/20 0.45
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CNR1 P21554 1/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7529284 0.94 NR1H4 (0.54) NR1H4NPC1KMT2AMEN1HTT
SCHEMBL5724755 0.86 ALDH1A1 (0.55) NR1H4NPC1KMT2AMEN1HTT
SCHEMBL12773624 0.85 NR1H4 (0.53) NR1H4NPC1KMT2AMEN1HTT
SCHEMBL10732696 0.85 NPC1 (0.49) NR1H4NPC1KMT2AMEN1HTT
SCHEMBL24270281 0.83 KMT2A (0.53) NR1H4NPC1KMT2AMEN1RAB9A
SCHEMBL15290436 0.83 NR1H4 (0.50) NR1H4NPC1KMT2AMEN1HTT
SCHEMBL25189609 0.83 KMT2A (0.51) NR1H4KMT2AMEN1TSHRCYP1A2
SCHEMBL16370682 0.83 TSHR (0.47) NR1H4NPC1TSHRCYP1A2CYP2D6
SCHEMBL7873314 0.82 MEN1 (0.45) NR1H4NPC1KMT2AMEN1HTT
SCHEMBL4116525 0.81 NR1H4 (0.47) NR1H4NPC1KMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1722633-B1 Use of a insecticidal composition againt mosquitoes, namely for impregnation of mosquito nets INST RECH POUR LE DÉVELOPPEMENT IRD (FR) 2014-06-18 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
US-7793920-B2 barrier against insect; the net structure made of polymer fibers is impregnated with an insecticide; preventing the low flying insects from entering open-air area; black color; invisible to certain insects VESTERGAARD SA (CH) 2010-09-14 US claimed
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US claimed
US-20070122437-A1 Novel insecticide composition and use thereof particularly for impregnating mosquito nets, fly screens and the like INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) 2007-05-31 US claimed
EP-1722633-A2 NEW INSECTICIDE COMPOSITION AND ITS USE, NAMELY FOR IMPREGNATION OF MOSQUITO NETS Institut de Recherche pour le Développement ( IRD) (FR) 2006-11-22 EP claimed
EP-1697578-A2 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-09-06 EP claimed
WO-2005079577-A2 NOVEL INSECTICIDE COMPOSITION AND USE THEREOF PARTICULARLY FOR IMPREGNATING MOSQUITO NETS, FLY SCREENS AND THE LIKE INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) 2005-09-01 WO claimed
WO-2005064072-A2 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 WO claimed
US-20050132500-A1 Composition for impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2005-06-23 US claimed
EP-1411764-B1 A FENCING DISEASE CONTROL TEXTILES APS (DK) 2004-12-29 EP claimed
EP-1411764-A1 A FENCING Disease Control Textiles APS (DK) 2004-04-28 EP claimed
US-20040004210-A1 Fencing VESTERGAARD SA (CH) 2004-01-08 US claimed
WO-2003003827-A1 A FENCING DISEASE CONTROL TEXTILES APS (DK) 2003-01-16 WO claimed
WO-2001037662-A1 COMPOSITION FOR IMPREGNATION OF FABRICS AND NETTINGS DCT APS (DK) 2001-05-31 WO claimed
US-4226883-A Carbamate derivatives and method for manufacture thereof YAMAMOTO IZURU 1980-10-07 US claimed
CN-118302524-A High molecular weight modified dsRNA compositions 纳诺索尔公司 2024-07-05 CN disclosed
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP disclosed
EP-0214546-A2 Insecticidal composition for use in agriculture and horticulture NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-03-18 EP disclosed
US-3981903-A PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests GAP43, GRN, DDT NR1H4 4759/4885NPC1 4516/4885KMT2A 1837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.