SCHEMBL7873314

SCHEMBL7873314

CNC(=O)Oc1ccc(C)c(C)c1.Cc1ccc(CNC(=O)O)cc1C

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HTT P42858 1/20 0.45
NPC1 O15118 4/20 0.44
RAB9A P51151 3/20 0.44
NR1H4 Q96RI1 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HSP90AA1 P07900 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6733303 0.84 TDP1 (0.50) NPC1TDP1L3MBTL1SMN1; SMN2ACHE
SCHEMBL7529284 0.84 NR1H4 (0.54) MEN1KMT2AHTTNPC1RAB9A
SCHEMBL63141 0.84 SMN1; SMN2 (0.51) KMT2ANPC1TDP1L3MBTL1SMN1; SMN2
SCHEMBL29600800 0.84 SMN1; SMN2 (0.51) KMT2ANPC1TDP1L3MBTL1SMN1; SMN2
SCHEMBL585949 0.82 NR1H4 (0.58) MEN1KMT2AHTTNPC1RAB9A
SCHEMBL28266629 0.73 TOP2A (0.44) HTTNPC1RAB9ANR1H4HSP90AA1
SCHEMBL11475470 0.73 ACHE (0.50) KMT2ANPC1TDP1L3MBTL1SMN1; SMN2
SCHEMBL7873316 0.73 ALDH1A1 (0.42) MEN1KMT2ANPC1TDP1L3MBTL1
Diamide SCHEMBL27878374 0.72 ACHE (0.43) NPC1TDP1L3MBTL1SMN1; SMN2ACHE
SCHEMBL25189609 0.71 KMT2A (0.51) MEN1KMT2ARAB9ANR1H4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564945-B1 A method of controlling harmful insects BAYER AGROCHEM KK (JP) 2001-01-24 EP disclosed
US-6063393-A RODS OR PINS TO BE PRESSED INTO PLANTS NIHON BAYER AGROCHEM K.K. (JP) 2000-05-16 US disclosed
EP-0564945-A1 A method of controlling harmful insects NIHON BAYER AGROCHEM K.K. (JP) 1993-10-13 EP disclosed