Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585658 | 0.83 | GAA (0.38) | ALDH1A1MAPTTSHRHSD17B10KDM4E | |
| SCHEMBL7987623 | 0.79 | HPGD (0.52) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL586865 | 0.79 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL586866 | 0.79 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3751574 | 0.77 | KMT2A (0.58) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL2282810 | 0.77 | KMT2A (0.58) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL2391124 | 0.77 | KMT2A (0.52) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL584306 | 0.77 | KMT2A (0.52) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7423554 | 0.76 | KDM4E (0.48) | MAPTHPGDRECQLEPHX1KDM4E | |
| SCHEMBL3787646 | 0.76 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417124-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | Eli Lilly and Company (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117979-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | ELI LILLY AND COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |